HCAR3/HCAR2 Antibody (PACO05630)
- SKU:
- PACO05630
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | HCAR3/HCAR2 Antibody (PACO05630) |
| Antibody SKU: | PACO05630 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | ELISA:1:10000, WB:1:500-1:2000, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from the C-terminal region of human HM74. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | HCAR3; GPR109B; HCA3; HM74B; NIACR2; Hydroxycarboxylic acid receptor 3; G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; Niacin receptor 2; Nicotinic acid receptor 2; HCAR2; GPR109A; HCA2; |
| UniProt Protein Function: | GPR109B: Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 12q24.31 Cellular Component: cell junction; integral to plasma membrane; plasma membrane |
| UniProt Code: | P49019 |
| NCBI GenInfo Identifier: | 519668680 |
| NCBI Gene ID: | 8843 |
| NCBI Accession: | P49019.3 |
| UniProt Secondary Accession: | P49019,Q8NGE4, A8K4G5, B2R830, E9PI97, |
| UniProt Related Accession: | P49019 |
| Molecular Weight: | 44,478 Da |
| NCBI Full Name: | Hydroxycarboxylic acid receptor 3 |
| NCBI Synonym Full Names: | hydroxycarboxylic acid receptor 3 |
| NCBI Official Symbol: | HCAR3 |
| NCBI Official Synonym Symbols: | HCA3; HM74; PUMAG; Puma-g; GPR109B |
| NCBI Protein Information: | hydroxycarboxylic acid receptor 3 |
| UniProt Protein Name: | Hydroxycarboxylic acid receptor 3 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; Niacin receptor 2; Nicotinic acid receptor 2 |
| Protein Family: | Hydroxycarboxylic acid receptor |
| UniProt Gene Name: | HCAR3 |
| UniProt Entry Name: | HCAR3_HUMAN |
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