The limbic system-associated membrane protein (LAMP) is a cell surface glycoprotein expressed by cortical and subcortical regions of the mammalian CNS that comprise or receive direct projections from limbic system structures. The 64-68-kDa glycoprotein limbic system-associated membrane protein (LsAMP) is expressed on the surface of somata and proximal dendrites of neurons. These areas perform cognitive and autonomic functions, also learning and memory. The functional analysis indicates that LsAMP acts as a selective adhesion molecule, serving as a guidance cue for specific patterns of connectivity, which underlies the normal development of the limbic system. In animal studies there have been found that rats with increased level of anxiety had 1.6-fold higher expression of LsAMP gene in the periaqueductal gray compared to rats with low level of anxiety, indicating a possible role of LsAMP in the regulation of anxiety.
Product Name:
HAGH/GLO2/Glyoxalase II Recombinant Protein (RPES3454)
Product Code:
RPES3454
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
GLO2,GLX2,GLXII,HAGH1
Accession:
Q16775-2
Sequence:
Met 1-Asp 260
Fusion tag:
C-His
Endotoxin:
Please contact us for more information.
Protein Construction:
A DNA sequence encoding the mature form of human HAGH isoform 2 (Q16775-2) (Met 1-Asp 260) was fused with a polyhistide tag at the C-terminus
Purity:
> 96 % as determined by reducing SDS-PAGE.
Mol Mass:
30.2 kDa
AP Mol Mass:
19 kDa
Formulation:
Lyophilized from sterile 20mM Tris, 0.15 M NaCl, 10% glycerol, pH 7.5
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
