Description
Antibody Name: | GPS1 Antibody |
Antibody SKU: | PACO03960 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from human CSN1 around the non-phosphorylation site of S454. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | GPS1; COPS1; CSN1; COP9 signalosome complex subunit 1; SGN1; Signalosome subunit 1; G protein pathway suppressor 1; GPS-1; JAB1-containing signalosome subunit 1; Protein MFH |
UniProt Protein Function: | COPS1: a protein that suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction. Shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. |
UniProt Protein Details: | Protein type:G protein regulator, misc. Chromosomal Location of Human Ortholog: 17q25.3 Cellular Component: signalosome; cytoplasm; nucleus Molecular Function:protein binding; GTPase inhibitor activity Biological Process: cullin deneddylation; JNK cascade; cell cycle; inactivation of MAPK activity |
NCBI Summary: | This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q13098 |
NCBI GenInfo Identifier: | 223590263 |
NCBI Gene ID: | 2873 |
NCBI Accession: | Q13098.4 |
UniProt Secondary Accession: | Q13098,Q8NA10, Q9BWL1, |
UniProt Related Accession: | Q13098 |
Molecular Weight: | 491 |
NCBI Full Name: | COP9 signalosome complex subunit 1 |
NCBI Synonym Full Names: | G protein pathway suppressor 1 |
NCBI Official Symbol: | GPS1 |
NCBI Official Synonym Symbols: | CSN1; COPS1 |
NCBI Protein Information: | COP9 signalosome complex subunit 1; SGN1; GPS-1; signalosome subunit 1; COP9 signalosome subunit 1; JAB1-containing signalosome subunit 1 |
UniProt Protein Name: | COP9 signalosome complex subunit 1 |
UniProt Synonym Protein Names: | G protein pathway suppressor 1; GPS-1; JAB1-containing signalosome subunit 1; Protein MFH |
UniProt Gene Name: | GPS1 |
UniProt Entry Name: | CSN1_HUMAN |