| UniProt Protein Function: | GMPPA: This gene is thought to encode a GDP-mannose pyrophosphorylase. This enzyme catalyzes the reaction which converts mannose-1-phosphate and GTP to GDP-mannose which is involved in the production of N-linked oligosaccharides. [provided by RefSeq, Jul 2008]Protein type: Transferase; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - fructose and mannose; EC 2.7.7.13Chromosomal Location of Human Ortholog: 2q35Cellular Component: cytoplasmMolecular Function: nucleotidyltransferase activityBiological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; GDP-mannose biosynthetic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modificationDisease: Alacrima, Achalasia, And Mental Retardation Syndrome |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is thought to encode a GDP-mannose pyrophosphorylase. This enzyme catalyzes the reaction which converts mannose-1-phosphate and GTP to GDP-mannose which is involved in the production of N-linked oligosaccharides. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96IJ6 |
| NCBI GenInfo Identifier: | 119591162 |
| NCBI Gene ID: | 29926 |
| NCBI Accession: | EAW70756.1 |
| UniProt Secondary Accession: | Q96IJ6,Q53GI0, Q9NWC3, Q9Y5P5, A6NJ74, A8K3Q6, B3KMT4 |
| UniProt Related Accession: | Q96IJ6 |
| Molecular Weight: | 46,291 Da |
| NCBI Full Name: | GDP-mannose pyrophosphorylase A, isoform CRA_b |
| NCBI Synonym Full Names: | GDP-mannose pyrophosphorylase A |
| NCBI Official Symbol: | GMPPA |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | mannose-1-phosphate guanyltransferase alpha; mannose-1-phosphate guanylyltransferase (GDP); GTP-mannose-1-phosphate guanylyltransferase alpha |
| UniProt Protein Name: | Mannose-1-phosphate guanyltransferase alpha |
| UniProt Synonym Protein Names: | GDP-mannose pyrophosphorylase A; GTP-mannose-1-phosphate guanylyltransferase alpha |
| Protein Family: | Mannose-1-phosphate guanyltransferase |
| UniProt Gene Name: | GMPPA |
| UniProt Entry Name: | GMPPA_HUMAN |
