| UniProt Protein Function: | GDAP1L1: The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene. [provided by RefSeq, Feb 2012]Chromosomal Location of Human Ortholog: 20q12 |
| UniProt Protein Details: | |
| NCBI Summary: | The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene. [provided by RefSeq, Feb 2012] |
| UniProt Code: | Q96MZ0 |
| NCBI GenInfo Identifier: | 38257738 |
| NCBI Gene ID: | 78997 |
| NCBI Accession: | Q96MZ0.2 |
| UniProt Secondary Accession: | Q96MZ0,Q5TE60, Q68CW7, Q9BQJ7, Q9BQV4, Q9BWJ4, Q9H3Y2 Q9H4G5, B7Z621 |
| UniProt Related Accession: | Q96MZ0 |
| Molecular Weight: | |
| NCBI Full Name: | Ganglioside-induced differentiation-associated protein 1-like 1 |
| NCBI Synonym Full Names: | ganglioside induced differentiation associated protein 1-like 1 |
| NCBI Official Symbol: | GDAP1L1 |
| NCBI Official Synonym Symbols: | dJ881L22.1; dJ995J12.1.1 |
| NCBI Protein Information: | ganglioside-induced differentiation-associated protein 1-like 1; GDAP1-L1 |
| UniProt Protein Name: | Ganglioside-induced differentiation-associated protein 1-like 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ganglioside-induced differentiation-associated protein |
| UniProt Gene Name: | GDAP1L1 |
| UniProt Entry Name: | GD1L1_HUMAN |
