GAS7 Antibody (PACO51530)
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주문- SKU:
- PACO51530
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GAS7 Antibody (PACO51530) |
Antibody SKU: | PACO51530 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Recombinant Human Growth arrest-specific protein 7 protein (1-153AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Mouse brain tissue, Rat brain tissue. All lanes: GAS7 antibody at 2.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 55, 48, 40 kDa. Observed band size: 55 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human melanoma using PACO51530 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human brain tissue using PACO51530 at dilution of 1:100. |
Background: | May play a role in promoting maturation and morphological differentiation of cerebellar neurons. |
Synonyms: | Growth arrest-specific protein 7 (GAS-7), GAS7, KIAA0394 |
UniProt Protein Function: | GAS7: May play a role in promoting maturation and morphological differentiation of cerebellar neurons. A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell development/differentiation; Actin-binding; Transcription factor; Oncoprotein Chromosomal Location of Human Ortholog: 17p13.1 Cellular Component: ruffle; cytoplasm; actin filament Molecular Function:actin filament binding; transcription factor activity Biological Process: regulation of cell shape; actin filament bundle formation; regulation of transcription, DNA-dependent; actin filament polymerization; cell cycle arrest; neurite morphogenesis |
NCBI Summary: | Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described. [provided by RefSeq, Jul 2008] |
UniProt Code: | O60861 |
NCBI GenInfo Identifier: | 218512092 |
NCBI Gene ID: | 8522 |
NCBI Accession: | O60861.3 |
UniProt Related Accession: | O60861 |
Molecular Weight: | Observed: 50 kDaPredicted: 55 kDa |
NCBI Full Name: | Growth arrest-specific protein 7 |
NCBI Synonym Full Names: | growth arrest specific 7 |
NCBI Official Symbol: | GAS7 |
NCBI Protein Information: | growth arrest-specific protein 7 |
UniProt Protein Name: | Growth arrest-specific protein 7 |
Protein Family: | Growth arrest-specific protein |
UniProt Gene Name: | GAS7 |
UniProt Entry Name: | GAS7_HUMAN |