FUOM Antibody (PACO25300)
- SKU:
- PACO25300
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | FUOM Antibody (PACO25300) |
| Antibody SKU: | PACO25300 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Fucose mutarotase protein (1-134AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO25300 at dilution of 1:100. |
 | Immunofluorescence staining of HepG2 cells with PACO25300 at 1:140, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human liver tissue using PACO25300 at dilution of 1:100. |
| Background: | Involved in the interconversion between alpha- and beta-L-fucoses. L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%), the beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases. Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes. |
| Synonyms: | Fucose mutarotase (EC 5.1.3.29), FUOM, C10orf125 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | A2VDF0 |
| NCBI GenInfo Identifier: | 148596947 |
| NCBI Gene ID: | 282969 |
| NCBI Accession: | NP_001091953.1 |
| UniProt Secondary Accession: | A2VDF0 |
| UniProt Related Accession: | A2VDF0 |
| Molecular Weight: | |
| NCBI Full Name: | fucose mutarotase isoform 1 |
| NCBI Synonym Full Names: | fucose mutarotase |
| NCBI Official Symbol: | FUOM |
| NCBI Official Synonym Symbols: | FUCU; FucM; C10orf125 |
| NCBI Protein Information: | fucose mutarotase |
| UniProt Protein Name: | Fucose mutarotase |
| UniProt Synonym Protein Names: | |
| Protein Family: | Fucose mutarotase |
| UniProt Gene Name: | FUOM |
| UniProt Entry Name: | FUCM_HUMAN |
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