FHL3 Antibody (PACO16355)
- SKU:
- PACO16355
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | FHL3 Antibody (PACO16355) |
| Antibody SKU: | PACO16355 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human FHL3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO16355(FHL3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO16355(FHL3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE β chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene. |
| Synonyms: | four and a half LIM domains 3 |
| NCBI Summary: | The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q13643 |
| NCBI GenInfo Identifier: | 54112385 |
| NCBI Gene ID: | 2275 |
| NCBI Accession: | NP_004459.2 |
| UniProt Secondary Accession: | Q13643,Q6I9T0, Q9BVA2, D3DPT6, |
| UniProt Related Accession: | Q13643 |
| Molecular Weight: | 31,192 Da |
| NCBI Full Name: | four and a half LIM domains protein 3 isoform 1 |
| NCBI Synonym Full Names: | four and a half LIM domains 3 |
| NCBI Official Symbol: | FHL3 |
| NCBI Official Synonym Symbols: | SLIM2 |
| NCBI Protein Information: | four and a half LIM domains protein 3 |
| UniProt Protein Name: | |
| Protein Family: | Four and a half LIM domains protein |
| UniProt Gene Name: |
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