FEZ1 Antibody (PACO09279)
- SKU:
- PACO09279
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | FEZ1 Antibody (PACO09279) |
Antibody SKU: | PACO09279 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human FEZ1 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | fasciculation and elongation protein zeta 1 (zygin I); |
UniProt Protein Function: | FEZ1: May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules. Belongs to the zygin family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 11q24.2 Cellular Component: microtubule cytoskeleton; centrosome; microtubule; mitochondrion; axon; cytoplasm; dendrite; plasma membrane Molecular Function:protein binding; gamma-tubulin binding; protein kinase C binding; protein N-terminus binding Biological Process: establishment of mitochondrion localization; axon guidance; nervous system development; transport; cell adhesion |
NCBI Summary: | This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q99689 |
NCBI GenInfo Identifier: | 13431526 |
NCBI Gene ID: | 9638 |
NCBI Accession: | Q99689.1 |
UniProt Secondary Accession: | Q99689,O00679, O00728, Q6IBI7, |
UniProt Related Accession: | Q99689 |
Molecular Weight: | 12,074 Da |
NCBI Full Name: | Fasciculation and elongation protein zeta-1 |
NCBI Synonym Full Names: | fasciculation and elongation protein zeta 1 (zygin I) |
NCBI Official Symbol: | FEZ1 |
NCBI Protein Information: | fasciculation and elongation protein zeta-1; zygin I; zygin-1 |
UniProt Protein Name: | Fasciculation and elongation protein zeta-1 |
UniProt Synonym Protein Names: | Zygin I; Zygin-1 |
Protein Family: | Fasciculation and elongation protein |
UniProt Gene Name: | FEZ1 |
UniProt Entry Name: | FEZ1_HUMAN |