Dopamine beta-Hydroxylase Recombinant Protein (RPES5077)

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SKU:
RPES5077
Product type:
Recombinant Protein
Host species:
HEK293 Cells
Reactivity:
Human
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Description

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Dopamine beta-Hydroxylase Recombinant Protein

DBH is a 290 kDa copper-containing oxygenase. It can be detected in noradrenergic nerve terminals of the central and peripheral nervous systems, and is also expressed in chromaffin cells of the adrenal medulla. DBH contains our identical subunits, and its activity requires ascorbate as a cofactor. It functions in in the synthesis of small-molecule neurotransmitters that is membrane-bound, making norepinephrine the only transmitter synthesized inside vesicles. DBH has been shown to be associated with decision making and addictive behaviors such as alcohol and smoking, attention deficit hyperactivity disorder, and also with neurological diseases such as Schizophrenia and Alzheimer's.

Product Name:Dopamine beta-Hydroxylase Recombinant Protein (RPES5077)
Product Code:RPES5077
Size:10µg
Species:Human
Expressed Host:HEK293 Cells
Synonyms:DBM
Accession:P09172
Sequence:Ser26-Gly603
Fusion tag:N-His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:A DNA sequence encoding the human DBH (P09172) (Ser26-Gly603) was expressed with an N-terminal polyhistidine tag.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:67.3 kDa
AP Mol Mass:68 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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