DGKI Antibody (PACO23177)
- SKU:
- PACO23177
- Product type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DGKI Antibody (PACO23177) |
Antibody SKU: | PACO23177 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IF:1:100-1:500 |
Species Reactivity: | Human, Rat |
Immunogen: | Synthesized peptide derived from C-terminal of human DGKI. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from 293 cells, using DGKI antibody. |
![]() | Immunofluorescence analysis of HeLa cells, using DGKI antibody. |
Background: | This gene is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration. |
Synonyms: | DAG kinase iota; DGK-IOTA; DGK-iota; DGKI; EC 2.7.1.107 |
UniProt Protein Function: | DGKI: a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Kinase, lipid; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - glycerolipid; Motility/polarity/chemotaxis; EC 2.7.1.107 Chromosomal Location of Human Ortholog: 7q32.3-q33 Cellular Component: cytoplasm; dendritic spine; nucleoplasm; nucleus; plasma membrane; protein complex; synapse Molecular Function:diacylglycerol kinase activity; protein binding Biological Process: platelet activation |
NCBI Summary: | This gene is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration. [provided by RefSeq, Jul 2008] |
UniProt Code: | O75912 |
NCBI GenInfo Identifier: | 12643642 |
NCBI Gene ID: | 9162 |
NCBI Accession: | O75912.1 |
UniProt Secondary Accession: | O75912,Q9NZ49, A4D1Q9, |
UniProt Related Accession: | O75912 |
Molecular Weight: | 116,997 Da |
NCBI Full Name: | Diacylglycerol kinase iota |
NCBI Synonym Full Names: | diacylglycerol kinase iota |
NCBI Official Symbol: | DGKI |
NCBI Official Synonym Symbols: | DGK-IOTA |
NCBI Protein Information: | diacylglycerol kinase iota |
UniProt Protein Name: | Diacylglycerol kinase iota |
UniProt Synonym Protein Names: | Diglyceride kinase iota; DGK-iota |
Protein Family: | Diacylglycerol kinase |
UniProt Gene Name: | DGKI |
UniProt Entry Name: | DGKI_HUMAN |
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