Cytotoxin 4 Antibody (PACO34622)
- SKU:
- PACO34622
- Product type:
- Antibody
- Reactivity:
- Naja atra
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | Cytotoxin 4 Antibody (PACO34622) |
| Antibody SKU: | PACO34622 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Naja atra |
| Immunogen: | Recombinant Naja atra Cytotoxin 4 protein (22-81AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Basic protein that bind to cell membrane and depolarizes cardiomyocytes. This cytotoxin also shows lytic activities, but 2-fold more important than that of CTX-A2. It binds to the integrin alpha-V/beta-3 with a moderate affinity. Inhibits protein kinase C. It may interact with sulfatides in the cell membrane, which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It also may target the mitochondrial membrane and induces mitochondrial swelling and fragmentation. |
| Synonyms: | Cytotoxin 4 (CTX-4M) (CTX4) (Cardiotoxin A4) (CTX A4) (Cardiotoxin analog IV) (CTX IV) |
| UniProt Protein Function: | Basic protein that bind to cell membrane and depolarizes cardiomyocytes. This cytotoxin also shows lytic activities, but 2-fold more important than that of CTX-A2. It binds to the integrin alpha-V/beta-3 with a moderate affinity. Inhibits protein kinase C. It may interact with sulfatides in the cell membrane, which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It also may target the mitochondrial membrane and induces mitochondrial swelling and fragmentation. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P01443 |
| NCBI GenInfo Identifier: | 2851458 |
| NCBI Gene ID: | |
| NCBI Accession: | P01443.2 |
| UniProt Secondary Accession: | P01443 |
| UniProt Related Accession: | P01443 |
| Molecular Weight: | 22.8 kDa |
| NCBI Full Name: | Cytotoxin 4 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Cytotoxin 4 |
| UniProt Synonym Protein Names: | Cardiotoxin A4 |
| Protein Family: | Cytotoxin |
| UniProt Gene Name: | CTX IV |
| UniProt Entry Name: | 3SA4_NAJAT |
Related Products
