Cynomolgus PD-L2/B7-DC/CD273 Recombinant Protein (RPES2939)
- SKU:
- RPES2939
- Product type:
- Recombinant Protein
- Host species:
- Human Cells
- Reactivity:
- Cynomolgus
Frequently bought together:
Description
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Cynomolgus PD-L2/B7-DC/CD273 Recombinant Protein
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Product Name: | Cynomolgus PD-L2/B7-DC/CD273 Recombinant Protein (RPES2939) |
Product Code: | RPES2939 |
Size: | 10µg |
Species: | Cynomolgus |
Expressed Host: | Human Cells |
Synonyms: | Programmed Cell Death 1 Ligand 2, PD-1 Ligand 2, PD-L2, PDCD1 Ligand 2, Programmed Death Ligand 2, Butyrophilin B7-DC, B7-DC, CD273, PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2 |
Accession: | A4GW30 |
Sequence: | Leu20-Pro219 |
Fusion tag: | C-Fc |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Cynomolgus PD-L2 is produced by our Mammalian expression system and the target gene encoding Leu20-Pro219 is expressed with a Fc tag at the C-terminus. |
Purity: | > 95% as determined by reducing SDS-PAGE. |
Mol Mass: | 49.5 kDa |
AP Mol Mass: | 60-90 kDa |
Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS,pH 7.4. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |