Ctsg Antibody (PACO26029)
- SKU:
- PACO26029
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | Ctsg Antibody (PACO26029) |
| Antibody SKU: | PACO26029 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Cathepsin G protein (21-261AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movement and mitosis. |
| Synonyms: | Cathepsin G (EC 3.4.21.20) (Vimentin-specific protease) (VSP), Ctsg |
| UniProt Protein Function: | CTSG: Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride. Belongs to the peptidase S1 family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; EC 3.4.21.20; Protease Cellular Component: cytoplasm; extracellular matrix; extracellular space; intermediate filament; intracellular membrane-bound organelle; membrane; nucleus; plasma membrane; secretory granule Molecular Function:heparin binding; hydrolase activity; peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity Biological Process: defense response to fungus; defense response to Gram-positive bacterium; immune response; positive regulation of immune response; protein amino acid phosphorylation; protein processing; proteolysis; response to lipopolysaccharide |
| NCBI Summary: | This gene encodes a member of the peptidase S1 (chymotrypsin) family of serine endopeptidases. The encoded preproprotein is proteolytically processed to generate a mature protein product. This product appears to play a role in host defense, including inflammation and antigen processing. Homozygous knockout mice for this gene exhibit enhanced susceptibility to bacterial and fungal infection. [provided by RefSeq, Aug 2015] |
| UniProt Code: | P28293 |
| NCBI GenInfo Identifier: | 6681083 |
| NCBI Gene ID: | 13035 |
| NCBI Accession: | NP_031826.1 |
| UniProt Related Accession: | P28293 |
| Molecular Weight: | 42.9 kDa |
| NCBI Full Name: | cathepsin G preproprotein |
| NCBI Synonym Full Names: | cathepsin G |
| NCBI Official Symbol: | Ctsg |
| NCBI Official Synonym Symbols: | VSP; CatG |
| NCBI Protein Information: | cathepsin G |
| UniProt Protein Name: | Cathepsin G |
| UniProt Synonym Protein Names: | Vimentin-specific protease; VSP |
| Protein Family: | Cathepsin |
| UniProt Gene Name: | Ctsg |
| UniProt Entry Name: | CATG_MOUSE |
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