CSH1 Antibody (PACO16481)
- SKU:
- PACO16481
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | CSH1 Antibody (PACO16481) |
| Antibody SKU: | PACO16481 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human CSH1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO16481(CSH1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human placenta tissue, Human breast infiltrative duct tissue, Primary antibody: PACO16481(CSH1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO16481(CSH1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. |
| Synonyms: | chorionic somatomammotropin hormone 1 |
| UniProt Protein Function: | CSH1: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. Belongs to the somatotropin/prolactin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 17q24.2 Cellular Component: extracellular region Molecular Function:hormone activity; metal ion binding |
| NCBI Summary: | The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P0DML2 |
| NCBI GenInfo Identifier: | 190034 |
| NCBI Gene ID: | 1442 |
| NCBI Accession: | AAA98621.1 |
| UniProt Secondary Accession: | P0DML2,P01243, Q0VDB1, Q14407, |
| UniProt Related Accession: | P0DML2 |
| Molecular Weight: | 25,020 Da |
| NCBI Full Name: | placental lactogen |
| NCBI Synonym Full Names: | chorionic somatomammotropin hormone 1 (placental lactogen) |
| NCBI Official Symbol: | CSH1 |
| NCBI Official Synonym Symbols: | PL; CSA; CS-1; CSMT; hCS-1; hCS-A |
| NCBI Protein Information: | chorionic somatomammotropin hormone 1; choriomammotropin; placental lactogen; chorionic somatomammotropin A; chorionic somatomammotropin-1 |
| UniProt Protein Name: | Chorionic somatomammotropin hormone 1 |
| UniProt Synonym Protein Names: | Lactogen; Placental lactogen; PL |
| UniProt Gene Name: | CSH1 |
| UniProt Entry Name: | CSH1_HUMAN |
| Antibodies | ELISA Kits |
| Anti-CSH1 Antibody (CAB14528) | Human PL (Pancreatic Lipase) CLIA Kit (HUES01177) |
| Anti-CSH1 Antibody (CAB1972) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Anti-CSH1 Antibody (CAB14528)
Anti-Placental lactogen (CSH1) Antibody (CAB19258)
Human Placental Lactogen / CSH1 ELISA Kit
