| UniProt Protein Function: | COX7A2: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase VIIa family.Protein type: Energy Metabolism - oxidative phosphorylation; Mitochondrial; EC 1.9.3.1; OxidoreductaseChromosomal Location of Human Ortholog: 6q12Cellular Component: mitochondrial respiratory chainMolecular Function: cytochrome-c oxidase activity |
| UniProt Protein Details: | |
| NCBI Summary: | Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009] |
| UniProt Code: | O60397 |
| NCBI GenInfo Identifier: | 8928009 |
| NCBI Gene ID: | 1347 |
| NCBI Accession: | O60397.1 |
| UniProt Secondary Accession: | O60397,P14406 |
| UniProt Related Accession: | O60397,P14406 |
| Molecular Weight: | 11,841 Da |
| NCBI Full Name: | Putative cytochrome c oxidase subunit 7A3, mitochondrial |
| NCBI Synonym Full Names: | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) |
| NCBI Official Symbol: | COX7A2 |
| NCBI Official Synonym Symbols: | VIIAL; COX7AL; COX7AL1; COXVIIAL; COXVIIa-L |
| NCBI Protein Information: | cytochrome c oxidase subunit 7A2, mitochondrial |
| UniProt Protein Name: | Putative cytochrome c oxidase subunit 7A3, mitochondrial |
| UniProt Synonym Protein Names: | Cytochrome c oxidase subunit VIIa 3 |
| Protein Family: | Cytochrome c oxidase |
| UniProt Gene Name: | COX7A2P2 |
| UniProt Entry Name: | COX7S_HUMAN |
