| UniProt Protein Function: | CLEC9A: Functions as an endocytic receptor on a small subset of myeloid cells and induces intracellular signaling via spleen tyrosine kinase (Syk). Acts as a receptor for necrotic cells and can mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.Protein type: Membrane protein, integral; Receptor, misc.Chromosomal Location of Human Ortholog: 12p13.2Cellular Component: cell surfaceBiological Process: positive regulation of cytokine secretion; receptor-mediated endocytosis |
| UniProt Protein Details: | |
| NCBI Summary: | CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008] |
| UniProt Code: | Q6UXN8 |
| NCBI GenInfo Identifier: | 73917794 |
| NCBI Gene ID: | 283420 |
| NCBI Accession: | Q6UXN8.1 |
| UniProt Secondary Accession: | Q6UXN8,B0ZBM2 |
| UniProt Related Accession: | Q6UXN8 |
| Molecular Weight: | 27,324 Da |
| NCBI Full Name: | C-type lectin domain family 9 member A |
| NCBI Synonym Full Names: | C-type lectin domain family 9 member A |
| NCBI Official Symbol: | CLEC9A |
| NCBI Official Synonym Symbols: | CD370; DNGR1; DNGR-1; UNQ9341 |
| NCBI Protein Information: | C-type lectin domain family 9 member A |
| UniProt Protein Name: | C-type lectin domain family 9 member A |
| UniProt Synonym Protein Names: | |
| Protein Family: | C-type lectin domain family |
| UniProt Gene Name: | CLEC9A |
| UniProt Entry Name: | CLC9A_HUMAN |
