CEBPD/E Transcription Factor Activity Assay
- SKU:
- TFAB00197
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- CEBPD/E
- Reactivity:
- Human
- Mouse
- Rat
Description
CEBPD/E Transcription Factor Activity Assay
The CEBPD (CCAAT/Enhancer Binding Protein Delta) Transcription Factor Activity Assay Kit is a cutting-edge tool designed for the accurate detection and measurement of CEBPD transcription factor activity in various biological samples. This kit offers high sensitivity and specificity, ensuring precise and reliable results for researchers studying gene regulation and cellular signaling pathways.CEBPD is a key transcription factor that plays a crucial role in regulating gene expression and controlling various cellular processes such as inflammation, immune response, and cell differentiation.
Dysregulation of CEBPD has been linked to various diseases including cancer, inflammatory disorders, and metabolic diseases, highlighting its importance as a potential therapeutic target.The CEBPD Transcription Factor Activity Assay Kit provides researchers with a powerful tool to study the role of CEBPD in disease pathogenesis and to explore its potential as a target for novel therapeutic interventions. With its user-friendly protocol and robust performance, this assay kit is ideal for a wide range of research applications in the field of molecular biology and biomedical science.
| Product Name: | CEBPD/E Transcription Factor Activity Assay |
| Product Code: | TFAB00197 |
| Target: | CEBPD/E |
| Synonyms: | Nuclear factor NF-IL6-beta |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie CEBPD/E transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | C/EBP-delta: C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages. Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha. Interacts with SPI1/PU.1. Interacts with PRDM16. Belongs to the bZIP family. C/EBP subfamily. |
| UniProt Protein Details: | Protein type:DNA-binding; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 8p11.2-p11.1 Cellular Component: nucleus Biological Process: transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010] |
| UniProt Code: | P49716 |
| NCBI GenInfo Identifier: | 160332350 |
| NCBI Gene ID: | 1052 |
| NCBI Accession: | P49716.2 |
| UniProt Secondary Accession: | P49716,Q03484, |
| UniProt Related Accession: | P49716 |
| Molecular Weight: | 269 |
| NCBI Full Name: | CCAAT/enhancer-binding protein delta |
| NCBI Synonym Full Names: | CCAAT/enhancer binding protein (C/EBP), delta |
| NCBI Official Symbol: | CEBPD |
| NCBI Official Synonym Symbols: | CELF; CRP3; C/EBP-delta; NF-IL6-beta |
| NCBI Protein Information: | CCAAT/enhancer-binding protein delta; c/EBP delta; nuclear factor NF-IL6-beta |
| UniProt Protein Name: | CCAAT/enhancer-binding protein delta |
| UniProt Synonym Protein Names: | Nuclear factor NF-IL6-beta; NF-IL6-beta |
| Protein Family: | CCAAT/enhancer-binding protein |
| UniProt Gene Name: | CEBPD |
| UniProt Entry Name: | CEBPD_HUMAN |
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