UniProt Protein Function: | CEACAM6: Belongs to the immunoglobulin superfamily. CEA family |
UniProt Protein Details: | Protein type:Membrane protein, GPI anchor; Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: extracellular space; integral to plasma membrane; plasma membrane Molecular Function:protein binding Biological Process: cell-cell signaling; leukocyte migration; signal transduction |
NCBI Summary: | This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014] |
UniProt Code: | P40199 |
NCBI GenInfo Identifier: | 296439410 |
NCBI Gene ID: | 4680 |
NCBI Accession: | P40199.3 |
UniProt Secondary Accession: | P40199,Q13774, Q14920, Q53XP7, |
UniProt Related Accession: | P40199 |
Molecular Weight: | 37,195 Da |
NCBI Full Name: | Carcinoembryonic antigen-related cell adhesion molecule 6 |
NCBI Synonym Full Names: | carcinoembryonic antigen related cell adhesion molecule 6 |
NCBI Official Symbol: | CEACAM6 |
NCBI Official Synonym Symbols: | NCA; CEAL; CD66c |
NCBI Protein Information: | carcinoembryonic antigen-related cell adhesion molecule 6 |
UniProt Protein Name: | Carcinoembryonic antigen-related cell adhesion molecule 6 |
UniProt Synonym Protein Names: | Non-specific crossreacting antigen; Normal cross-reacting antigen; CD_antigen: CD66c |
Protein Family: | Carcinoembryonic antigen-related cell adhesion molecule |
UniProt Gene Name: | CEACAM6 |
UniProt Entry Name: | CEAM6_HUMAN |