CEACAM6 Antibody (PACO18695)
- SKU:
- PACO18695
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | CEACAM6 Antibody (PACO18695) |
| Antibody SKU: | PACO18695 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human CEACAM6 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO18695(CEACAM6 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18695(CEACAM6 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Carcinoembryonic antigen (CEA; MIM 114890) is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma. An apparent lack of absolute cancer specificity for CEA probably results in part from the presence in normal and neoplastic tissues of antigens that share antigenic determinants with the 180-kD form of CEA (Barnett et al., 1988 [PubMed 3220478]). For background information on the CEA family of genes, see CEACAM1 (MIM 109770). |
| Synonyms: | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| UniProt Protein Function: | CEACAM6: Belongs to the immunoglobulin superfamily. CEA family |
| UniProt Protein Details: | Protein type:Membrane protein, GPI anchor; Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: extracellular space; integral to plasma membrane; plasma membrane Molecular Function:protein binding Biological Process: cell-cell signaling; leukocyte migration; signal transduction |
| NCBI Summary: | This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014] |
| UniProt Code: | P40199 |
| NCBI GenInfo Identifier: | 296439410 |
| NCBI Gene ID: | 4680 |
| NCBI Accession: | P40199.3 |
| UniProt Secondary Accession: | P40199,Q13774, Q14920, Q53XP7, |
| UniProt Related Accession: | P40199 |
| Molecular Weight: | 37,195 Da |
| NCBI Full Name: | Carcinoembryonic antigen-related cell adhesion molecule 6 |
| NCBI Synonym Full Names: | carcinoembryonic antigen related cell adhesion molecule 6 |
| NCBI Official Symbol: | CEACAM6 |
| NCBI Official Synonym Symbols: | NCA; CEAL; CD66c |
| NCBI Protein Information: | carcinoembryonic antigen-related cell adhesion molecule 6 |
| UniProt Protein Name: | Carcinoembryonic antigen-related cell adhesion molecule 6 |
| UniProt Synonym Protein Names: | Non-specific crossreacting antigen; Normal cross-reacting antigen; CD_antigen: CD66c |
| Protein Family: | Carcinoembryonic antigen-related cell adhesion molecule |
| UniProt Gene Name: | CEACAM6 |
| UniProt Entry Name: | CEAM6_HUMAN |
| Antibodies |
| Anti-CEACAM6 Antibody (CAB8440) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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