CASZ1 Antibody (PACO61646)
- SKU:
- PACO61646
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | CASZ1 Antibody (PACO61646) |
| Antibody SKU: | PACO61646 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Zinc finger protein castor homolog 1 protein (127-266AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Jurkat whole cell lysate. All lanes: CASZ1 antibody at 4.8µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 191, 125 kDa. Observed band size: 191 kDa. |
 | IHC image of PACO61646 diluted at 1:100 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Transcriptional activator. Involved in vascular assembly and morphogenesis through direct transcriptional regulation of EGFL7. |
| Synonyms: | Zinc finger protein castor homolog 1, Castor-related protein, Putative survival-related protein, Zinc finger protein 693, CASZ1, CST, SRG, ZNF693 |
| UniProt Protein Function: | CASZ1: Probable transcription factor. 2 isoforms of the human protein are produced by alternative splicing.Protein type: C2H2-type zinc finger protein; Motility/polarity/chemotaxis; Transcription factorChromosomal Location of Human Ortholog: 1p36.22Cellular Component: nucleoplasm; intracellular membrane-bound organelle; cytoplasmMolecular Function: DNA binding; metal ion bindingBiological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; multicellular organismal development |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a zinc finger transcription factor. The encoded protein may function as a tumor suppressor, and single nucleotide polymorphisms in this gene are associated with blood pressure variation. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012] |
| UniProt Code: | Q86V15 |
| NCBI GenInfo Identifier: | 119709834 |
| NCBI Gene ID: | 54897 |
| NCBI Accession: | NP_001073312.1 |
| UniProt Secondary Accession: | Q86V15,Q078S9, Q2EN02, Q5T9S1, Q6ZNM8, Q8WX49, Q8WX50 Q9BT16, Q9NXC6 |
| UniProt Related Accession: | Q86V15 |
| Molecular Weight: | 190,069 Da |
| NCBI Full Name: | zinc finger protein castor homolog 1 isoform a |
| NCBI Synonym Full Names: | castor zinc finger 1 |
| NCBI Official Symbol: | CASZ1 |
| NCBI Official Synonym Symbols: | CST; SRG; CAS11; ZNF693; dJ734G22.1 |
| NCBI Protein Information: | zinc finger protein castor homolog 1; survival-related; castor-related protein; zinc finger protein 693; castor homolog 1, zinc finger |
| UniProt Protein Name: | Zinc finger protein castor homolog 1 |
| UniProt Synonym Protein Names: | Castor-related protein; Putative survival-related protein; Zinc finger protein 693 |
| Protein Family: | Zinc finger protein castor |
| UniProt Gene Name: | CASZ1 |
| UniProt Entry Name: | CASZ1_HUMAN |
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