BATF Antibody (PACO21865)
- SKU:
- PACO21865
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | BATF Antibody (PACO21865) |
Antibody SKU: | PACO21865 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized peptide derived from internal of human BATF. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Meyer N.P., Mamm. Genome 9:849-852(1998). |
Clonality: | Polyclonal |
Conjugate: | Non-conjugated |
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using BATF antibody. |
Synonyms: | B-ATF; SF-HT-activated gene 2 protein; SFA-2; |
UniProt Protein Function: | BATF: a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. Functions as a negative regulator of AP-1 mediated transcription by binding to Jun proteins. Jun/B-ATF heterodimers bind DNA preferentially at the 12-O-tetradecanoylphorbol-13- acetate response element (TRE) and weaker at the cAMP responsive region (CRE), but are transcriptionally inert. |
UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 14q24.3 Cellular Component: cytoplasm; nucleus Molecular Function:protein binding; sequence-specific DNA binding; transcription factor activity Biological Process: cytokine production; defense response to protozoan; DNA damage response, signal transduction by p53 class mediator; isotype switching; lymphoid progenitor cell differentiation; myeloid dendritic cell differentiation; response to DNA damage stimulus; T-helper 2 cell differentiation |
NCBI Summary: | The protein encoded by this gene is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q16520 |
NCBI GenInfo Identifier: | 32171340 |
NCBI Gene ID: | 10538 |
NCBI Accession: | Q16520.1 |
UniProt Related Accession: | Q16520 |
Molecular Weight: | 14,120 Da |
NCBI Full Name: | Basic leucine zipper transcriptional factor ATF-like |
NCBI Synonym Full Names: | basic leucine zipper ATF-like transcription factor |
NCBI Official Symbol: | BATF |
NCBI Official Synonym Symbols: | SFA2; B-ATF; BATF1; SFA-2 |
NCBI Protein Information: | basic leucine zipper transcriptional factor ATF-like |
UniProt Protein Name: | Basic leucine zipper transcriptional factor ATF-like |
UniProt Synonym Protein Names: | B-cell-activating transcription factor; B-ATF; SF-HT-activated gene 2 protein; SFA-2 |
Protein Family: | Basic leucine zipper transcriptional factor |
UniProt Gene Name: | BATF |
UniProt Entry Name: | BATF_HUMAN |