B3GALT1 Antibody (PACO22194)
- SKU:
- PACO22194
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | B3GALT1 Antibody (PACO22194) |
Antibody SKU: | PACO22194 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized peptide derived from internal of human B3GALT1. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from HepG2 cells, Jurkat cells, COLO cells and HUVEC cells, using B3GALT1 antibody. |
Background: | Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues. |
Synonyms: | B3GT1; beta-1; 3-galactosyltransferase 1; beta-1; 3-GalTase 1 |
UniProt Protein Function: | Beta-1,3-galactosyltransferase that transfers galactose from UDP-alpha-D-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues. |
NCBI Summary: | This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is expressed exclusively in the brain. The encoded protein shows strict donor substrate specificity for UDP-galactose. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y5Z6 |
NCBI GenInfo Identifier: | 10304987 |
NCBI Gene ID: | 8708 |
NCBI Accession: | NP_066191.1 |
UniProt Secondary Accession: | Q9Y5Z6,Q53SS2, D3DPB8, |
UniProt Related Accession: | Q9Y5Z6 |
Molecular Weight: | 36 KD |
NCBI Full Name: | beta-1,3-galactosyltransferase 1 |
NCBI Synonym Full Names: | beta-1,3-galactosyltransferase 1 |
NCBI Official Symbol: | B3GALT1 |
NCBI Official Synonym Symbols: | beta3Gal-T1 |
NCBI Protein Information: | beta-1,3-galactosyltransferase 1 |
UniProt Protein Name: | Beta-1,3-galactosyltransferase 1 |
UniProt Synonym Protein Names: | UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1 |
Protein Family: | Beta-1,3-galactosyltransferase |
UniProt Gene Name: | B3GALT1 |
Antibodies | ELISA Kits |
B3GALT1 Antibody (PACO01738) | Human B3GALT1 ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |