Anti-ZNF638 Antibody (CAB15821)
- SKU:
- CAB15821
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Antibody Name: | Anti-ZNF638 Antibody |
Antibody SKU: | CAB15821 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ZNF638 (NP_001239542.1). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse |
Positive Samples: | Mouse brain |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ZNF638 (NP_001239542.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MSRP RFNP RGDF PLQR PRAP NPSG MRPP GPFM RPGS MGLP RFYP AGRA RGIP HRFA GHES YQNM GPQR MNVQ VTQH RTDP RLTK EKLD FHEA QQKK GKPH GSRW DDEP HISA SVAV KQSS VTQV TEQS PKVQ SRYT KESA SSIL ASFG LSNE DLEE LSRY PDEQ LTPE NMPL ILRD IRMR KMGR RLPN LPSQ SRNK ETLG SEAV SSNV IDYG HASK YGYT EDPL EVRI YDPE IPTD EVEN EFQS QQNI SASV PNPN VICN SMFP VEDV FRQM DFPG ESSN NRSF FSVE SGTK MSGL HISG |
Gene ID: | 27332 |
Uniprot: | Q14966 |
Cellular Location: | Nucleus speckle |
Calculated MW: | 92kDa/119kDa/128kDa/218kDa/220kDa |
Observed MW: | 140kDa |
Synonyms: | ZNF638, NP220, ZFML, Zfp638 |
Background: | The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. |
UniProt Protein Function: | ZNF638: Early regulator of adipogenesis that works as a transcription cofactor of CEBPs, controlling the expression of PPARG and probably of other proadipogenic genes, such as SREBF1. Binds to cytidine clusters in double-stranded DNA. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding; RNA-binding Chromosomal Location of Human Ortholog: 2p13.1 Cellular Component: nucleoplasm; intracellular membrane-bound organelle; cytoplasm; nuclear speck Molecular Function:zinc ion binding; RNA binding; double-stranded DNA binding; nucleotide binding Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; RNA splicing |
NCBI Summary: | The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q14966 |
NCBI GenInfo Identifier: | 62526045 |
NCBI Gene ID: | 27332 |
NCBI Accession: | NP_001014972.1 |
UniProt Related Accession: | Q14966 |
Molecular Weight: | |
NCBI Full Name: | zinc finger protein 638 isoform 1 |
NCBI Synonym Full Names: | zinc finger protein 638 |
NCBI Official Symbol: | ZNF638 |
NCBI Official Synonym Symbols: | ZFML; NP220; Zfp638 |
NCBI Protein Information: | zinc finger protein 638 |
UniProt Protein Name: | Zinc finger protein 638 |
UniProt Synonym Protein Names: | Cutaneous T-cell lymphoma-associated antigen se33-1; CTCL-associated antigen se33-1; Nuclear protein 220; Zinc finger matrin-like protein |
UniProt Gene Name: | ZNF638 |
UniProt Entry Name: | ZN638_HUMAN |