Anti-ZNF10 Antibody (CAB15737)
- SKU:
- CAB15737
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| Antibody Name: | Anti-ZNF10 Antibody |
| Antibody SKU: | CAB15737 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human ZNF10 (NP_056209.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HT-1080 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human ZNF10 (NP_056209.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDAK SLTA WSRT LVTF KDVF VDFT REEW KLLD TAQQ IVYR NVML ENYK NLVS LGYQ LTKP DVIL RLEK GEEP WLVE REIH QETH PDSE TAFE IKSS VSSR SIFK DKQS CDIK MEGM ARND LWYL SLEE VWKC RDQL DKYQ ENPE RHLR QVAF TQKK VLTQ ERVS ESGK YGGN CLLP AQLV LREY FHKR DSHT KSLK HDLV |
| Gene ID: | 7556 |
| Uniprot: | P21506 |
| Cellular Location: | Nucleus |
| Calculated MW: | 66kDa |
| Observed MW: | 60kDa |
| Synonyms: | ZNF10, KOX1 |
| Background: | The protein encoded by this gene contains a C2H2 zinc finger, and has been shown to function as a transcriptional repressor. The Kruppel-associated box (KRAB) domain of this protein is found to be responsible for its transcriptional repression activity. RING finger containing protein TIF1 was reported to interact with the KRAB domain, and may serve as a mediator for the repression activity of this protein. |
| UniProt Protein Function: | ZNF10: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. |
| UniProt Protein Details: | Protein type:C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 12q24.33 Cellular Component: nucleus Molecular Function:protein binding |
| NCBI Summary: | The protein encoded by this gene contains a C2H2 zinc finger, and has been shown to function as a transcriptional repressor. The Kruppel-associated box (KRAB) domain of this protein is found to be responsible for its transcriptional repression activity. RING finger containing protein TIF1 was reported to interact with the KRAB domain, and may serve as a mediator for the repression activity of this protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P21506 |
| NCBI GenInfo Identifier: | 55977778 |
| NCBI Gene ID: | 7556 |
| NCBI Accession: | P21506.3 |
| UniProt Secondary Accession: | P21506,Q8TC91, B2RBS1, |
| UniProt Related Accession: | P21506 |
| Molecular Weight: | 66,455 Da |
| NCBI Full Name: | Zinc finger protein 10 |
| NCBI Synonym Full Names: | zinc finger protein 10 |
| NCBI Official Symbol: | ZNF10 |
| NCBI Official Synonym Symbols: | KOX1 |
| NCBI Protein Information: | zinc finger protein 10 |
| UniProt Protein Name: | Zinc finger protein 10 |
| UniProt Synonym Protein Names: | Zinc finger protein KOX1 |
| Protein Family: | Zinc finger protein |
| UniProt Gene Name: | ZNF10 |
| UniProt Entry Name: | ZNF10_HUMAN |
 | Western blot analysis of extracts of HT-1080 cells, using ZNF10 antibody (CAB15737) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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