Anti-ZHX2 Antibody (CAB18235)
- SKU:
- CAB18235
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Antibody Name: | Anti-ZHX2 Antibody |
Antibody SKU: | CAB18235 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human ZHX2. |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | U-251MG, 293T, Raji, LO2, Mouse brain |
Immunogen: | Recombinant protein of human ZHX2. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 22882 |
Uniprot: | Q9Y6X8 |
Cellular Location: | |
Calculated MW: | 92kDa |
Observed MW: | 120kDa |
Synonyms: | RAF, AFR1, ZHX2 |
Background: | The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. |
UniProt Protein Function: | ZHX2: Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. Belongs to the ZHX family. |
UniProt Protein Details: | Protein type:C2H2-type zinc finger protein; Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 8q24.13 Cellular Component: cytoplasm; nucleoplasm; nucleus; plasma membrane Molecular Function:identical protein binding; protein binding; protein heterodimerization activity; protein homodimerization activity; transcription corepressor activity; transcription factor activity Biological Process: negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent |
NCBI Summary: | The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y6X8 |
NCBI GenInfo Identifier: | 44888553 |
NCBI Gene ID: | 22882 |
NCBI Accession: | Q9Y6X8.1 |
UniProt Related Accession: | Q9Y6X8 |
Molecular Weight: | 92,307 Da |
NCBI Full Name: | Zinc fingers and homeoboxes protein 2 |
NCBI Synonym Full Names: | zinc fingers and homeoboxes 2 |
NCBI Official Symbol: | ZHX2 |
NCBI Official Synonym Symbols: | RAF; AFR1 |
NCBI Protein Information: | zinc fingers and homeoboxes protein 2 |
UniProt Protein Name: | Zinc fingers and homeoboxes protein 2 |
UniProt Synonym Protein Names: | Alpha-fetoprotein regulator 1; AFP regulator 1; Regulator of AFP; Zinc finger and homeodomain protein 2 |
Protein Family: | Zinc fingers and homeoboxes protein |
UniProt Gene Name: | ZHX2 |
UniProt Entry Name: | ZHX2_HUMAN |