Anti-ZDHHC7 Antibody (CAB17981)
- SKU:
- CAB17981
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| Antibody Name: | Anti-ZDHHC7 Antibody |
| Antibody SKU: | CAB17981 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human ZDHHC7. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | A-431, PC-3, Mouse lung |
| Immunogen: | Recombinant protein of human ZDHHC7. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 55625 |
| Uniprot: | Q9NXF8 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 33kDa |
 | Western blot - ZDHHC7 Rabbit pAb (CAB17981) |
| Synonyms: | DHHC7, SERZ-B, SERZ1, ZNF370, ZDHHC7 |
| Background: |
| UniProt Protein Function: | ZDHHC7: Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and thereby regulate their synaptic clustering and/or cell surface stability. Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptors. Belongs to the DHHC palmitoyltransferase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; EC 2.3.1.225; Transferase; Membrane protein, multi-pass; Palmitoyltransferase Chromosomal Location of Human Ortholog: 16q24.1 Cellular Component: Golgi apparatus; intracellular membrane-bound organelle; nucleolus; nucleoplasm; nucleus Molecular Function:palmitoyltransferase activity Biological Process: peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine; protein palmitoylation |
| UniProt Code: | Q9NXF8 |
| NCBI GenInfo Identifier: | 116242853 |
| NCBI Gene ID: | 55625 |
| NCBI Accession: | Q9NXF8.2 |
| UniProt Secondary Accession: | Q9NXF8,Q8WV42, Q9NVD8, D3DUM1, |
| UniProt Related Accession: | Q9NXF8 |
| Molecular Weight: | 38,917 Da |
| NCBI Full Name: | Palmitoyltransferase ZDHHC7 |
| NCBI Synonym Full Names: | zinc finger DHHC-type containing 7 |
| NCBI Official Symbol: | ZDHHC7 |
| NCBI Official Synonym Symbols: | DHHC7; SERZ1; SERZ-B; ZNF370 |
| NCBI Protein Information: | palmitoyltransferase ZDHHC7 |
| UniProt Protein Name: | Palmitoyltransferase ZDHHC7 |
| UniProt Synonym Protein Names: | Zinc finger DHHC domain-containing protein 7 |
| Protein Family: | Palmitoyltransferase |
| UniProt Gene Name: | ZDHHC7 |
| UniProt Entry Name: | ZDHC7_HUMAN |
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