Anti-XPNPEP1 Antibody (CAB15327)
- SKU:
- CAB15327
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-XPNPEP1 Antibody |
| Antibody SKU: | CAB15327 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 44-240 of human XPNPEP1 (NP_065116.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | 293T, Mouse heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 44-240 of human XPNPEP1 (NP_065116.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MPPK VTSE LLRQ LRQA MRNS EYVT EPIQ AYII PSGD AHQS EYIA PCDC RRAF VSGF DGSA GTAI ITEE HAAM WTDG RYFL QAAK QMDS NWTL MKMG LKDT PTQE DWLV SVLP EGSR VGVD PLII PTDY WKKM AKVL RSAG HHLI PVKE NLVD KIWT DRPE RPCK PLLT LGLD YTGI SWKD KVAD LRLK MAER NVMW F |
| Gene ID: | 7511 |
| Uniprot: | Q9NQW7 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 67kDa/69kDa/72kDa/74kDa |
| Observed MW: | 90kDa |
| Synonyms: | XPNPEP1, APP1, SAMP, XPNPEP, XPNPEPL, XPNPEPL1 |
| Background: | This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | XPNPEP1: Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. Belongs to the peptidase M24B family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.4.11.9; Protease Chromosomal Location of Human Ortholog: 10q25.3 Cellular Component: cytoplasm Molecular Function:aminopeptidase activity; manganese ion binding; protein homodimerization activity Biological Process: proteolysis |
| NCBI Summary: | This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009] |
| UniProt Code: | Q9NQW7 |
| NCBI GenInfo Identifier: | 264681565 |
| NCBI Gene ID: | 7511 |
| NCBI Accession: | NP_001161076.1 |
| UniProt Related Accession: | Q9NQW7 |
| Molecular Weight: | |
| NCBI Full Name: | xaa-Pro aminopeptidase 1 isoform 2 |
| NCBI Synonym Full Names: | X-prolyl aminopeptidase 1 |
| NCBI Official Symbol: | XPNPEP1 |
| NCBI Official Synonym Symbols: | APP1; SAMP; XPNPEP; XPNPEPL; XPNPEPL1 |
| NCBI Protein Information: | xaa-Pro aminopeptidase 1 |
| UniProt Protein Name: | Xaa-Pro aminopeptidase 1 |
| UniProt Synonym Protein Names: | Aminoacylproline aminopeptidase; Cytosolic aminopeptidase P; Soluble aminopeptidase P; sAmp; X-Pro aminopeptidase 1; X-prolyl aminopeptidase 1, soluble |
| UniProt Gene Name: | XPNPEP1 |
| UniProt Entry Name: | XPP1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using XPNPEP1 antibody (CAB15327) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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