Anti-WFDC2 Antibody (CAB6788)
- SKU:
- CAB6788
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-WFDC2 Antibody |
| Antibody SKU: | CAB6788 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-124 of human WFDC2 (NP_006094.3). |
| Application: | IHC |
| Recommended Dilution: | IHC 1:100 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-124 of human WFDC2 (NP_006094.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LVSG TGAE KTGV CPEL QADQ NCTQ ECVS DSEC ADNL KCCS AGCA TFCS LPND KEGS CPQV NINF PQLG LCRD QCQV DSQC PGQM KCCR NGCG KVSC VTPN F |
| Gene ID: | 10406 |
| Uniprot: | Q14508 |
| Cellular Location: | Secreted |
| Calculated MW: | 8kDa/11kDa/12kDa |
| Observed MW: | Refer to figures |
| Synonyms: | WFDC2, EDDM4, HE4, WAP5, dJ461P17.6 |
| Background: | This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. |
| UniProt Protein Function: | WFDC2: a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 20q13.12 Cellular Component: extracellular space Molecular Function:serine-type endopeptidase inhibitor activity; aspartic-type endopeptidase inhibitor activity; endopeptidase inhibitor activity; cysteine protease inhibitor activity Biological Process: spermatogenesis; proteolysis |
| NCBI Summary: | This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q14508 |
| NCBI GenInfo Identifier: | 20141958 |
| NCBI Gene ID: | 10406 |
| NCBI Accession: | Q14508.2 |
| UniProt Secondary Accession: | Q14508,Q6IB27, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1 A2A2A5, A2A2A6, A6PVD5, |
| UniProt Related Accession: | Q14508 |
| Molecular Weight: | 124 |
| NCBI Full Name: | WAP four-disulfide core domain protein 2 |
| NCBI Synonym Full Names: | WAP four-disulfide core domain 2 |
| NCBI Official Symbol: | WFDC2 |
| NCBI Official Synonym Symbols: | HE4; WAP5; EDDM4; dJ461P17.6 |
| NCBI Protein Information: | WAP four-disulfide core domain protein 2; epididymal protein 4; epididymal secretory protein E4; putative protease inhibitor WAP5; WAP domain containing protein HE4-V4; major epididymis-specific protein E4; epididymis-specific, whey-acidic protein type, four-disulfide core |
| UniProt Protein Name: | WAP four-disulfide core domain protein 2 |
| UniProt Synonym Protein Names: | Epididymal secretory protein E4; Major epididymis-specific protein E4; Putative protease inhibitor WAP5 |
| Protein Family: | WAP four-disulfide core domain protein |
| UniProt Gene Name: | WFDC2 |
| UniProt Entry Name: | WFDC2_HUMAN |
 | Immunohistochemistry of paraffin-embedded human stomach using WFDC2 antibody (CAB6788) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse stomach using WFDC2 antibody (CAB6788) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat heart using WFDC2 antibody (CAB6788) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human prostate using WFDC2 antibody (CAB6788) at dilution of 1:100 (40x lens). |
Related Products
Anti-HE4/WFDC2 Antibody (CAB3276)
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
