Anti-WFDC1 Antibody (CAB17193)
- SKU:
- CAB17193
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-WFDC1 Antibody |
| Antibody SKU: | CAB17193 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 111-220 of human WFDC1 (NP_067020.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | 293T, SGC-7901, Mouse brain, Mouse lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 111-220 of human WFDC1 (NP_067020.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PPVL DWLV QPKP RWLG GNGW LLDG PEEV LQAE ACST TEDG AEPL LCPS GYEC HILS PGDV AEGI PNRG QCVK QRRQ ADGR ILRH KLYK EYPE GDSK NVAE PGRG QQKH FQ |
| Gene ID: | 58189 |
| Uniprot: | Q9HC57 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 30kDa |
 | Western blot - WFDC1 Rabbit pAb (CAB17193) |
| Synonyms: | WFDC1, PS20 |
| Background: | This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | WFDC1: Has growth inhibitory activity. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 16q24.3 Cellular Component: extracellular space Biological Process: regulation of cell growth |
| NCBI Summary: | This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
| UniProt Code: | Q9HC57 |
| NCBI GenInfo Identifier: | 22096244 |
| NCBI Gene ID: | 58189 |
| NCBI Accession: | Q9HC57.2 |
| UniProt Secondary Accession: | Q9HC57,Q8NC27, Q9HAU1, D3DUL7, |
| UniProt Related Accession: | Q9HC57 |
| Molecular Weight: | 23,977 Da |
| NCBI Full Name: | WAP four-disulfide core domain protein 1 |
| NCBI Synonym Full Names: | WAP four-disulfide core domain 1 |
| NCBI Official Symbol: | WFDC1 |
| NCBI Official Synonym Symbols: | PS20 |
| NCBI Protein Information: | WAP four-disulfide core domain protein 1 |
| UniProt Protein Name: | WAP four-disulfide core domain protein 1 |
| UniProt Synonym Protein Names: | Prostate stromal protein ps20; ps20 growth inhibitor |
| Protein Family: | WAP four-disulfide core domain protein |
| UniProt Gene Name: | WFDC1 |
| UniProt Entry Name: | WFDC1_HUMAN |
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