Anti-WDR33 Antibody (CAB9531)
- SKU:
- CAB9531
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| Antibody Name: | Anti-WDR33 Antibody |
| Antibody SKU: | CAB9531 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human WDR33 (NP_001006623.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, HepG2, U-87MG, MCF7, Mouse testis, Mouse thymus, Rat thymus, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human WDR33 (NP_001006623.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MATE IGSP PRFF HMPR FQHQ APRQ LFYK RPDF AQQQ AMQQ LTFD GKRM RKAV NRKT IDYN PSVI KYLE NRIW QRDQ RDMR AIQP DAGY YNDL VPPI GMLN NPMN AVTT KFVR TSTN KVKC PVFV VRWT PEGR RLVT GASS GEFT LWNG LTFN FETI LQAH DSPV RAMT WSHN DMWM LTAD HGGY VKYW QSNM NNVK MFQA |
| Gene ID: | 55339 |
| Uniprot: | Q9C0J8 |
| Cellular Location: | Nucleus |
| Calculated MW: | 30kDa/38kDa/145kDa |
| Observed MW: | 170kDa |
| Synonyms: | WDR33, NET14, WDC146 |
| Background: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| UniProt Protein Function: | Essential for both cleavage and polyadenylation of pre-mRNA 3' ends. |
| NCBI Summary: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9C0J8 |
| NCBI GenInfo Identifier: | 55743157 |
| NCBI Gene ID: | 55339 |
| NCBI Accession: | NP_001006623.1 |
| UniProt Secondary Accession: | Q9C0J8,Q05DP8, Q53FG9, Q587J1, Q69YF7, Q6NUQ0, Q9NUL1 |
| UniProt Related Accession: | Q9C0J8 |
| Molecular Weight: | 146kDa |
| NCBI Full Name: | pre-mRNA 3' end processing protein WDR33 isoform 2 |
| NCBI Synonym Full Names: | WD repeat domain 33 |
| NCBI Official Symbol: | WDR33 |
| NCBI Official Synonym Symbols: | NET14; WDC146 |
| NCBI Protein Information: | pre-mRNA 3' end processing protein WDR33 |
| UniProt Protein Name: | pre-mRNA 3' end processing protein WDR33 |
| UniProt Synonym Protein Names: | WD repeat-containing protein 33; WD repeat-containing protein WDC146 |
| Protein Family: | pre-mRNA 3' end processing protein |
| UniProt Gene Name: | WDR33 |
 | Western blot analysis of extracts of various cell lines, using WDR33 antibody (CAB9531) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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