Anti-WDR18 Antibody (CAB15875)
- SKU:
- CAB15875
- Product type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-WDR18 Antibody |
| Antibody SKU: | CAB15875 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 243-432 of human WDR18 (NP_077005.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: | A-549, Jurkat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 243-432 of human WDR18 (NP_077005.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DLFT WPGQ RERS FHPE QDAG KVFK GHRN QVTC LSVS TDGS VLLS GSHD ETVR LWDV QSKQ CIRT VALK GPVT NAAI LLAP VSML SSDF RPSL PLPH FNKH LLGA EHGD EPRH GGLT LRLG LHQQ GSEP SYLD RTEQ LQAV LCST MEKS VLGG QDQL RVRV TELE DEVR NLRK INRD LFDF STRF ITRP AK |
| Gene ID: | 57418 |
| Uniprot: | Q9BV38 |
| Cellular Location: | Cytoplasm, Nucleus, nucleoplasm |
| Calculated MW: | 47kDa |
| Observed MW: | 47kDa |
| Synonyms: | WDR18, Ipi3, R32184_1 |
| Background: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. |
| UniProt Protein Function: | WDR18: a WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: nucleoplasm Molecular Function:protein binding Biological Process: rRNA processing |
| NCBI Summary: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BV38 |
| NCBI GenInfo Identifier: | 37589023 |
| NCBI Gene ID: | 57418 |
| NCBI Accession: | BC001648 |
| UniProt Secondary Accession: | Q9BV38,O60390, Q9BWR2, |
| UniProt Related Accession: | Q9BV38 |
| Molecular Weight: | 47,405 Da |
| NCBI Full Name: | Homo sapiens WD repeat domain 18, mRNA |
| NCBI Synonym Full Names: | WD repeat domain 18 |
| NCBI Official Symbol: | WDR18 |
| NCBI Official Synonym Symbols: | Ipi3; R32184_1 |
| NCBI Protein Information: | WD repeat-containing protein 18 |
| UniProt Protein Name: | WD repeat-containing protein 18 |
| Protein Family: | WD repeat-containing protein |
| UniProt Gene Name: | WDR18 |
| UniProt Entry Name: | WDR18_HUMAN |
 | Western blot analysis of extracts of various cell lines, using WDR18 antibody (CAB15875) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 120s. |
 | Immunofluorescence analysis of U-2 OS cells using WDR18 antibody (CAB15875) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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