Anti-WBSCR16 Antibody (CAB14330)

(No reviews yet) Write a Review
SKU:
CAB14330
Product type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Frequently bought together:

Description

system_update_alt데이터시트system_update_alt안전 데이터시트
Antibody Name:Anti-WBSCR16 Antibody
Antibody SKU:CAB14330
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human WBSCR16 (NP_110425.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Raji, HeLa, LO2, Mouse liver, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human WBSCR16 (NP_110425.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MALV ALVA GARL GRRL SGPG LGRG HWTA AGRS RSRR EAAE AEAE VPVV QYVG ERAA RADR VFVW GFSF SGAL GVPS FVVP SSGP GPRA GARP RRRI QPVP YRLE LDQK ISSA ACGY GFTL LSSK TADV TKVW GMGL NKDS QLGF HRSR KDKT RGYE YVLE PSPV SLPL DRPQ ETRV LQVS CGRA HSLV LTDR EGVF SMGN NSYG QCGR KVVE NEIY SESH RVHR MQDF DG
Gene ID:81554
Uniprot:Q96I51
Cellular Location:
Calculated MW:38kDa/48kDa/49kDa
Observed MW:50kDa
Synonyms:RCC1L, WBSCR16, RCC1 like
Background:This gene encodes a protein containing regulator of chromosome condensation 1-like repeats. The encoded protein may function as a guanine nucleotide exchange factor. This gene is located in a region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:WBSCR16: a guanine-nucleotide exchange factor (GEF) factor for Ran, a nuclear GTP-binding protein. Its interaction with Ran probably plays an important role in the regulation of gene expression. Deleted in Williams syndrome, a multisystem developmental disorder. Contains six regulator of chromosome condensation (RCC1) domains.
UniProt Protein Details:

Protein type:Mitochondrial; GEFs, Ras; GEFs

Chromosomal Location of Human Ortholog: 7q11.23

Disease: Williams-beuren Syndrome

NCBI Summary:This gene encodes a protein containing regulator of chromosome condensation 1-like repeats. The encoded protein may function as a guanine nucleotide exchange factor. This gene is located in a region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
UniProt Code:Q96I51
NCBI GenInfo Identifier:116242843
NCBI Gene ID:81554
NCBI Accession:Q96I51.2
UniProt Secondary Accession:Q96I51,Q548B1, Q8IW88, Q8N572, Q9H0G7, D3DXK0, F5GX55 F5H6C7,
UniProt Related Accession:Q96I51
Molecular Weight:48,761 Da
NCBI Full Name:Williams-Beuren syndrome chromosomal region 16 protein
NCBI Synonym Full Names:RCC1 like
NCBI Official Symbol:RCC1L  
NCBI Official Synonym Symbols:WBSCR16  
NCBI Protein Information:Williams-Beuren syndrome chromosomal region 16 protein
UniProt Protein Name:Williams-Beuren syndrome chromosomal region 16 protein
UniProt Synonym Protein Names:RCC1-like G exchanging factor-like protein
UniProt Gene Name:WBSCR16  
UniProt Entry Name:WBS16_HUMAN
Anti-WBSCR16 Antibody (CAB14330)Western blot analysis of extracts of various cell lines, using WBSCR16 antibody (CAB14330) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.

0 Reviews

View AllClose

Related Products