Anti-WBP11 Antibody (CAB16191)

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SKU:
CAB16191
Product type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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Antibody Name:Anti-WBP11 Antibody
Antibody SKU:CAB16191
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human WBP11 (NP_057396.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:U-87MG, 293T, Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human WBP11 (NP_057396.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGRR STSS TKSG KFMN PTDQ ARKE ARKR ELKK NKKQ RMMV RAAV LKMK DPKQ IIRD MEKL DEME FNPV QQPQ LNEK VLKD KRKK LRET FERI LRLY EKEN PDIY KELR KLEV EYEQ KRAQ LSQY FDAV KNAQ HVEV ESIP
Gene ID:51729
Uniprot:Q9Y2W2
Cellular Location:Cytoplasm, Nucleus
Calculated MW:69kDa
Observed MW:115kDa
Synonyms:WBP11, NPWBP, PPP1R165, SIPP1, WBP-11
Background:This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.
UniProt Protein Function:Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity.
NCBI Summary:This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus. [provided by RefSeq, Jul 2008]
UniProt Code:Q9Y2W2
NCBI GenInfo Identifier:7706501
NCBI Gene ID:51729
NCBI Accession:NP_057396.1
UniProt Secondary Accession:Q9Y2W2,Q96AY8,
UniProt Related Accession:Q9Y2W2
Molecular Weight:69,998 Da
NCBI Full Name:WW domain-binding protein 11
NCBI Synonym Full Names:WW domain binding protein 11
NCBI Official Symbol:WBP11  
NCBI Official Synonym Symbols:NPWBP; SIPP1; WBP-11; PPP1R165  
NCBI Protein Information:WW domain-binding protein 11
UniProt Protein Name:WW domain-binding protein 11
UniProt Synonym Protein Names:Npw38-binding protein; NpwBP; SH3 domain-binding protein SNP70; Splicing factor that interacts with PQBP-1 and PP1
Protein Family:WW domain-binding protein
UniProt Gene Name:WBP11  
Anti-WBP11 Antibody (CAB16191)Western blot analysis of extracts of various cell lines, using WBP11 antibody (CAB16191) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-WBP11 Antibody (CAB16191)Western blot analysis of extracts of Mouse brain, using WBP11 antibody (CAB16191) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.

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