Anti-VIP Antibody (CAB1804)
- SKU:
- CAB1804
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-VIP Antibody |
| Antibody SKU: | CAB1804 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-170 of human VIP (NP_003372.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | BxPC-3, U-87MG, SH-SY5Y, Mouse spleen, Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-170 of human VIP (NP_003372.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | APSA LRLG DRIP FEGA NEPD QVSL KEDI DMLQ NALA ENDT PYYD VSRN ARHA DGVF TSDF SKLL GQLS AKKY LESL MGKR VSSN ISED PVPV KRHS DAVF TDNY TRLR KQMA VKKY LNSI LNGK RSSE GESP DFPE ELEK |
| Gene ID: | 7432 |
| Uniprot: | P01282 |
| Cellular Location: | Secreted |
| Calculated MW: | 19kDa |
| Observed MW: | 14kDa |
| Synonyms: | VIP, PHM27 |
| Background: | The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. |
| UniProt Protein Function: | VIP: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. Belongs to the glucagon family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 6q25.2 Cellular Component: extracellular region Molecular Function:hormone activity; neuropeptide hormone activity; protein binding Biological Process: body fluid secretion; G-protein coupled receptor protein signaling pathway; mRNA stabilization; positive regulation of cell proliferation; positive regulation of protein catabolic process; regulation of protein localization |
| NCBI Summary: | The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014] |
| UniProt Code: | P01282 |
| NCBI GenInfo Identifier: | 138574 |
| NCBI Gene ID: | 7432 |
| NCBI Accession: | P01282.1 |
| UniProt Secondary Accession: | P01282,Q5TCY8, Q5TCY9, Q96QK3, |
| UniProt Related Accession: | P01282 |
| Molecular Weight: | |
| NCBI Full Name: | VIP peptides |
| NCBI Synonym Full Names: | vasoactive intestinal peptide |
| NCBI Official Symbol: | VIP |
| NCBI Official Synonym Symbols: | PHM27 |
| NCBI Protein Information: | VIP peptides |
| UniProt Protein Name: | VIP peptides |
| UniProt Synonym Protein Names: | Intestinal peptide PHV-42Alternative name(s):Peptide histidine valine 42 |
| Protein Family: | VIP peptides |
| UniProt Gene Name: | VIP |
 | Western blot analysis of extracts of various cell lines, using VIP Antibody (CAB1804) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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