Anti-UTS2R Antibody (CAB2959)
- SKU:
- CAB2959
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-UTS2R Antibody |
| Antibody SKU: | CAB2959 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 280-389 of human UTS2R (NP_061822.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, Mouse brain, Mouse heart, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 280-389 of human UTS2R (NP_061822.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LAQY HQAP LAPR TARI VNYL TTCL TYGN SCAN PFLY TLLT RNYR DHLR GRVR GPGS GGGR GPVP SLQP RARF QRCS GRSL SSCS PQPT DSLV LAPA APAR PAPE GPRA PA |
| Gene ID: | 2837 |
| Uniprot: | Q9UKP6 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 42kDa |
| Observed MW: | 42kDa |
| Synonyms: | UTS2R, GPR14, UR-2-R, UTR, UTR2 |
| Background: |
| UniProt Protein Function: | UTS2R: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 17q25.3 Cellular Component: recycling endosome; membrane; early endosome; plasma membrane; integral to membrane Molecular Function:G-protein coupled receptor activity; urotensin II receptor activity Biological Process: response to drug; G-protein coupled receptor protein signaling pathway; positive regulation of angiogenesis; elevation of cytosolic calcium ion concentration; positive regulation of fibroblast proliferation; positive regulation of circadian sleep/wake cycle, REM sleep; negative regulation of glomerular filtration; regulation of vasodilation; blood circulation; positive regulation of vasoconstriction; negative regulation of blood pressure; signal transduction; positive regulation of cell growth; positive regulation of blood pressure |
| UniProt Code: | Q9UKP6 |
| NCBI GenInfo Identifier: | 8928474 |
| NCBI Gene ID: | 2837 |
| NCBI Accession: | Q9UKP6.1 |
| UniProt Related Accession: | Q9UKP6 |
| Molecular Weight: | |
| NCBI Full Name: | Urotensin-2 receptor |
| NCBI Synonym Full Names: | urotensin 2 receptor |
| NCBI Official Symbol: | UTS2R |
| NCBI Official Synonym Symbols: | UTR; UTR2; GPR14; UR-2-R |
| NCBI Protein Information: | urotensin-2 receptor |
| UniProt Protein Name: | Urotensin-2 receptor |
| UniProt Synonym Protein Names: | G-protein coupled receptor 14; Urotensin II receptor; UR-II-R |
| UniProt Gene Name: | UTS2R |
| UniProt Entry Name: | UR2R_HUMAN |
 | Western blot analysis of extracts of various cell lines, using UTS2R antibody (CAB2959) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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