Anti-UTP18 Antibody (CAB15441)
- SKU:
- CAB15441
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| Antibody Name: | Anti-UTP18 Antibody |
| Antibody SKU: | CAB15441 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-260 of human UTP18 (NP_057085.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, Jurkat, Mouse brain, Mouse kidney, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-260 of human UTP18 (NP_057085.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | RRLR QRNR LRLE EDKP AVER CLEE LVFG DVEN DEDA LLRR LRGP RVQE HEDS GDSE VENE AKGN FPPQ KKPV WVDE EDED EEMV DMMN NRFR KDMM KNAS ESKL SKDN LKKR LKEE FQHA MGGV PAWA ETTK RKTS SDDE SEED EDDL LQRT GNFI STST SLPR GILK MKNC QHAN AERP TVAR ISSV QFH |
| Gene ID: | 51096 |
| Uniprot: | Q9Y5J1 |
| Cellular Location: | Nucleus, nucleolus |
| Calculated MW: | 62kDa |
| Observed MW: | 60-70kDa |
| Synonyms: | UTP18, CGI-48, WDR50 |
| Background: |
| UniProt Protein Function: | WDR50: a nuclear WD40 repeat protein involved in nucleolar processing of pre-18S ribosomal RNA. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing, and cytoskeleton assembly. Belongs to the WD repeat UTP18 family. |
| UniProt Protein Details: | Protein type:RNA-binding; Nucleolus Chromosomal Location of Human Ortholog: 17q21.33 Cellular Component: small subunit processome; nucleolus; nucleus Biological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| UniProt Code: | Q9Y5J1 |
| NCBI GenInfo Identifier: | 118344456 |
| NCBI Gene ID: | 51096 |
| NCBI Accession: | NP_057085.2 |
| UniProt Related Accession: | Q9Y5J1 |
| Molecular Weight: | ~ 60-70kDa |
| NCBI Full Name: | U3 small nucleolar RNA-associated protein 18 homolog |
| NCBI Synonym Full Names: | UTP18 small subunit processome component |
| NCBI Official Symbol: | UTP18 |
| NCBI Official Synonym Symbols: | WDR50; CGI-48 |
| NCBI Protein Information: | U3 small nucleolar RNA-associated protein 18 homolog |
| UniProt Protein Name: | U3 small nucleolar RNA-associated protein 18 homolog |
| UniProt Synonym Protein Names: | WD repeat-containing protein 50 |
| Protein Family: | U3 small nucleolar RNA-associated protein |
| UniProt Gene Name: | UTP18 |
| UniProt Entry Name: | UTP18_HUMAN |
 | Western blot analysis of extracts of various cell lines, using UTP18 antibody (CAB15441) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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