Anti-USP40 Antibody (CAB15856)
- SKU:
- CAB15856
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| Antibody Name: | Anti-USP40 Antibody |
| Antibody SKU: | CAB15856 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1173-1247 of human USP40 (NP_060688.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, Mouse pancreas, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1173-1247 of human USP40 (NP_060688.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GDTI GVKN LLID DDDD FSTI RDDT GKEK QKQR ALGR RKSQ EALH EQSS YILS SAET PARP RAPE TSLS IHVG SFR |
| Gene ID: | 55230 |
| Uniprot: | Q9NVE5 |
| Cellular Location: | |
| Calculated MW: | 18kDa/140kDa/141kDa |
| Observed MW: | 140kDa |
| Synonyms: | USP40 |
| Background: | Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]). |
| UniProt Protein Function: | USP40: May be catalytically inactive. Belongs to the peptidase C19 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Ubiquitin-specific protease; Cell adhesion; Hydrolase; EC 3.4.19.12 Chromosomal Location of Human Ortholog: 2q37.1 Cellular Component: cytoplasm; nucleus |
| NCBI Summary: | Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9NVE5 |
| NCBI GenInfo Identifier: | 59803114 |
| NCBI Gene ID: | 55230 |
| NCBI Accession: | Q9NVE5.3 |
| UniProt Secondary Accession: | Q9NVE5,Q6NX38, Q70EL0, |
| UniProt Related Accession: | Q9NVE5 |
| Molecular Weight: | 141,558 Da |
| NCBI Full Name: | Ubiquitin carboxyl-terminal hydrolase 40 |
| NCBI Synonym Full Names: | ubiquitin specific peptidase 40 |
| NCBI Official Symbol: | USP40 |
| NCBI Protein Information: | ubiquitin carboxyl-terminal hydrolase 40 |
| UniProt Protein Name: | Ubiquitin carboxyl-terminal hydrolase 40 |
| UniProt Synonym Protein Names: | Deubiquitinating enzyme 40; Ubiquitin thioesterase 40; Ubiquitin-specific-processing protease 40 |
| Protein Family: | Ubiquitin carboxyl-terminal hydrolase |
| UniProt Gene Name: | USP40 |
| UniProt Entry Name: | UBP40_HUMAN |
 | Western blot analysis of extracts of various cell lines, using USP40 antibody (CAB15856) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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