Anti-UBQLN3 Antibody (CAB17697)
- SKU:
- CAB17697
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-UBQLN3 Antibody |
| Antibody SKU: | CAB17697 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 306-620 of human UBQLN3 (NP_059509.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | PC-3, Mouse testis, Rat testis, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 306-620 of human UBQLN3 (NP_059509.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | WTST HGGS GSRQ GRQD GDQD APDI RNRF PNFL GIIR LYDY LQQL HENP QSLG TYLQ GTAS ALSQ SQEP PPSV NRVP PSSP SSQE PGSG QPLP EESV AIKG RSSC PAFL RYPT ENST GQGG DQDG AGKS STGH STNL PDLV SGLG DSAN RVPF APLS FSPT AAIP GIPE PPWL PSPA YPRS LRPD GMNP APQL QDEI QPQL PLLM HLQA AMAN PRAL QALR QIEQ GLQV LATE APRL LLWF MPCL AGTG SVAG GIES REDP LMSE DPLP NPPP EVFP ALDS AELG FLSP PFLH MLQD LVST NPQQ LQPE AHFQ VQL |
| Gene ID: | 50613 |
| Uniprot: | Q9H347 |
| Cellular Location: | |
| Calculated MW: | 70kDa |
| Observed MW: | 71kDa |
 | Western blot - UBQLN3 Polyclonal Antibody (CAB17697) |
| Synonyms: | TUP-1, UBQLN3 |
| Background: | This gene encodes a ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and are thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis. It has been suggested that this gene may regulate cell-cycle progression during spermatogenesis, however, it has been shown that the ortholgous mouse gene is dispensable for embryonic development and spermatogenesis. [provided by RefSeq, Nov 2016] |
| UniProt Protein Function: | UBQLN3: |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 11p15 |
| NCBI Summary: | Summary: This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9H347 |
| NCBI GenInfo Identifier: | 8567418 |
| NCBI Gene ID: | 50613 |
| NCBI Accession: | NP_059509.1 |
| UniProt Secondary Accession: | Q9H347,Q9NRE0, |
| UniProt Related Accession: | Q9H347 |
| Molecular Weight: | 70,841 Da |
| NCBI Full Name: | ubiquilin-3 |
| NCBI Synonym Full Names: | ubiquilin 3 |
| NCBI Official Symbol: | UBQLN3 |
| NCBI Official Synonym Symbols: | TUP-1 |
| NCBI Protein Information: | ubiquilin-3 |
| UniProt Protein Name: | Ubiquilin-3 |
| Protein Family: | Ubiquilin |
| UniProt Gene Name: | UBQLN3 |
| UniProt Entry Name: | UBQL3_HUMAN |
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