Anti-TUSC2 Antibody (CAB7075)
- SKU:
- CAB7075
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| Antibody Name: | Anti-TUSC2 Antibody |
| Antibody SKU: | CAB7075 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human TUSC2 (NP_009206.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human TUSC2 (NP_009206.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGAS GSKA RGLW PFAS AAGG GGSE AAGA EQAL VRPR GRAV PPFV FTRR GSMF YDED GDLA HEFY EETI VTKN GQKR AKLR RVHK NLIP QGIV KLDH PRIH VDFP VILY EV |
| Gene ID: | 11334 |
| Uniprot: | O75896 |
| Cellular Location: | |
| Calculated MW: | 12kDa |
| Observed MW: | Refer to Figures |
| Synonyms: | TUSC2, C3orf11, FUS1, PAP, PDAP2 |
| Background: | This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. |
| UniProt Protein Function: | TUSC2: May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells. Belongs to the TUSC2 family. |
| UniProt Protein Details: | Protein type:Tumor suppressor Chromosomal Location of Human Ortholog: 3p21.3 Cellular Component: mitochondrion Biological Process: interleukin-15 production; cell proliferation; negative regulation of interleukin-17 production; regulation of mitochondrial membrane potential; cell-cell signaling; natural killer cell differentiation; response to defense-related host reactive oxygen species production; cell maturation; cell cycle; inflammatory response; positive regulation of interleukin-10 production; phagocytosis |
| NCBI Summary: | This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O75896 |
| NCBI GenInfo Identifier: | 7531123 |
| NCBI Gene ID: | 11334 |
| NCBI Accession: | O75896.3 |
| UniProt Secondary Accession: | O75896,B2R4Y9, |
| UniProt Related Accession: | O75896 |
| Molecular Weight: | 110 |
| NCBI Full Name: | Tumor suppressor candidate 2 |
| NCBI Synonym Full Names: | tumor suppressor candidate 2 |
| NCBI Official Symbol: | TUSC2 |
| NCBI Official Synonym Symbols: | PAP; FUS1; PDAP2; C3orf11 |
| NCBI Protein Information: | tumor suppressor candidate 2; fus-1 protein; fusion 1 protein; PDGFA associated protein 2; PDGFA-associated protein 2 |
| UniProt Protein Name: | Tumor suppressor candidate 2 |
| UniProt Synonym Protein Names: | Fusion 1 protein; Fus-1 protein; PDGFA-associated protein 2 |
| Protein Family: | Tumor suppressor candidate |
| UniProt Gene Name: | TUSC2 |
| UniProt Entry Name: | TUSC2_HUMAN |
 | Immunohistochemistry of paraffin-embedded rat brain using TUSC2 antibody (CAB7075) at dilution of 1:200 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse kidney using TUSC2 antibody (CAB7075) at dilution of 1:200 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse heart using TUSC2 antibody (CAB7075) at dilution of 1:200 (40x lens). |
 | Immunofluorescence analysis of U2OS cells using TUSC2 antibody (CAB7075). Blue: DAPI for nuclear staining. |
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