Anti-TUBB1 Antibody (CAB17779)
- SKU:
- CAB17779
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-TUBB1 Antibody |
| Antibody SKU: | CAB17779 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 362-451 of human TUBB1 (NP_110400.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse liver, Mouse heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 362-451 of human TUBB1 (NP_110400.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SMAA TFIG NNTA IQEI FNRV SEHF SAMF KRKA FVHW YTSE GMDI NEFG EAEN NIHD LVSE YQQF QDAK AVLE EDEE VTEE AEME PEDK GH |
| Gene ID: | 81027 |
| Uniprot: | Q9H4B7 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 50kDa |
 | Western blot - TUBB1 Polyclonal Antibody (CAB17779) |
| Synonyms: | TUBB1 |
| Background: | This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010] |
| UniProt Protein Function: | TUBB1: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Dimer of alpha and beta chains. Interacts with RANBP10. Hematopoietic cell-specific. Major isotype in leukocytes, where it represents 50% of all beta-tubulins. Belongs to the tubulin family. |
| UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 20q13.32 Cellular Component: cytoplasm Disease: Macrothrombocytopenia, Autosomal Dominant, Tubb1-related |
| NCBI Summary: | This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010] |
| UniProt Code: | Q9H4B7 |
| NCBI GenInfo Identifier: | 62903515 |
| NCBI Gene ID: | 81027 |
| NCBI Accession: | Q9H4B7.1 |
| UniProt Related Accession: | Q9H4B7 |
| Molecular Weight: | 50,327 Da |
| NCBI Full Name: | Tubulin beta-1 chain |
| NCBI Synonym Full Names: | tubulin beta 1 class VI |
| NCBI Official Symbol: | TUBB1 |
| NCBI Protein Information: | tubulin beta-1 chain |
| UniProt Protein Name: | Tubulin beta-1 chain |
| Protein Family: | Tubulin |
| UniProt Gene Name: | TUBB1 |
| UniProt Entry Name: | TBB1_HUMAN |
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