Anti-TSPAN31 Antibody (CAB14256)
- SKU:
- CAB14256
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-TSPAN31 Antibody |
| Antibody SKU: | CAB14256 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 95-175 of human TSPAN31 (NP_005972.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse brain, Mouse heart, Mouse kidney, Mouse liver, Rat ovary |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 95-175 of human TSPAN31 (NP_005972.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SCLA INRS KQTD VINA SWWV MSNK TRDE LERS FDCC GLFN LTTL YQQD YDFC TAIC KSQS PTCQ MCGE KFLK HSDE ALKI L |
| Gene ID: | 6302 |
| Uniprot: | Q12999 |
| Cellular Location: | Membrane, Multi-pass membrane protein |
| Calculated MW: | 23kDa |
| Observed MW: | 30kDa |
| Synonyms: | TSPAN31, SAS |
| Background: | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. |
| UniProt Protein Function: | TSPAN31: is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 12q13.3 Cellular Component: integral to plasma membrane; membrane Biological Process: cell surface receptor linked signal transduction; positive regulation of cell proliferation |
| NCBI Summary: | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q12999 |
| NCBI GenInfo Identifier: | 6174973 |
| NCBI Gene ID: | 6302 |
| NCBI Accession: | Q12999.1 |
| UniProt Secondary Accession: | Q12999,O00577, Q53X76, |
| UniProt Related Accession: | Q12999 |
| Molecular Weight: | 23,053 Da |
| NCBI Full Name: | Tetraspanin-31 |
| NCBI Synonym Full Names: | tetraspanin 31 |
| NCBI Official Symbol: | TSPAN31 |
| NCBI Official Synonym Symbols: | SAS |
| NCBI Protein Information: | tetraspanin-31 |
| UniProt Protein Name: | Tetraspanin-31 |
| UniProt Synonym Protein Names: | Sarcoma-amplified sequence |
| Protein Family: | Tetraspanin |
| UniProt Gene Name: | TSPAN31 |
| UniProt Entry Name: | TSN31_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TSPAN31 antibody (CAB14256) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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