Anti-TRNT1 Antibody (CAB17699)
- SKU:
- CAB17699
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-TRNT1 Antibody |
| Antibody SKU: | CAB17699 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 135-434 of human TRNT1 (NP_886552.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, A-549, Mouse kidney, Rat spleen, Rat lung, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 135-434 of human TRNT1 (NP_886552.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HAEV EFTT DWQK DAER RDLT INSM FLGF DGTL FDYF NGYE DLKN KKVR FVGH AKQR IQED YLRI LRYF RFYG RIVD KPGD HDPE TLEA IAEN AKGL AGIS GERI WVEL KKIL VGNH VNHL IHLI YDLD VAPY IGLP ANAS LEEF DKVS KNVD GFSP KPVT LLAS LFKV QDDV TKLD LRLK IAKE EKNL GLFI VKNR KDLI KATD SSDP LKPY QDFI IDSR EPDA TTRV CELL KYQG EHCL LKEM QQWS IPPF PVSG HDIR KVGI SSGK EIGA LLQQ LREQ WKKS GYQM EKDE LLSY IKKT |
| Gene ID: | 51095 |
| Uniprot: | Q96Q11 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 50kDa |
 | Western blot - TRNT1 Polyclonal Antibody (CAB17699) |
| Synonyms: | CCA1, CGI-47, MtCCA, RPEM, SIFD, TRNT1 |
| Background: | The protein encoded by this gene is a CCA-adding enzyme which belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. This essential enzyme functions by catalyzing the addition of the conserved nucleotide triplet CCA to the 3' terminus of tRNA molecules. Mutations in this gene result in sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| UniProt Protein Function: | TRNT1: Isoform 1: Adds and repairs the conserved 3'-CCA sequence necessary for the attachment of amino acids to the 3' terminus of tRNA molecules, using CTP and ATP as substrates. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 2.7.7.72; RNA processing; Mitochondrial; Transferase Chromosomal Location of Human Ortholog: 3p25.1 Cellular Component: intracellular; mitochondrial matrix; mitochondrion; nucleoplasm Molecular Function:ATP binding; RNA polymerase activity; tRNA adenylyltransferase activity; tRNA binding Biological Process: protein targeting to mitochondrion; tRNA 3'-end processing; tRNA 3'-terminal CCA addition Disease: Retinitis Pigmentosa And Erythrocytic Microcytosis; Sideroblastic Anemia With B-cell Immunodeficiency, Periodic Fevers, And Developmental Delay |
| NCBI Summary: | The protein encoded by this gene is a CCA-adding enzyme which belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. This essential enzyme functions by catalyzing the addition of the conserved nucleotide triplet CCA to the 3' terminus of tRNA molecules. Mutations in this gene result in sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| UniProt Code: | Q96Q11 |
| NCBI GenInfo Identifier: | 15214804 |
| NCBI Gene ID: | 51095 |
| NCBI Accession: | BC012537 |
| UniProt Secondary Accession: | Q96Q11,Q8ND57, Q9BS97, Q9Y362, A8K2Z6, B7WP13, C9JKA2 |
| UniProt Related Accession: | Q96Q11 |
| Molecular Weight: | 6,937 Da |
| NCBI Full Name: | Homo sapiens tRNA nucleotidyl transferase, CCA-adding, 1, mRNA |
| NCBI Synonym Full Names: | tRNA nucleotidyl transferase 1 |
| NCBI Official Symbol: | TRNT1 |
| NCBI Official Synonym Symbols: | CCA1; RPEM; SIFD; MtCCA; CGI-47 |
| NCBI Protein Information: | CCA tRNA nucleotidyltransferase 1, mitochondrial |
| UniProt Protein Name: | CCA tRNA nucleotidyltransferase 1, mitochondrial |
| UniProt Synonym Protein Names: | Mitochondrial tRNA nucleotidyl transferase, CCA-adding; mt CCA-adding enzyme; mt tRNA CCA-diphosphorylase; mt tRNA CCA-pyrophosphorylase; mt tRNA adenylyltransferase |
| Protein Family: | CCA tRNA nucleotidyltransferase |
| UniProt Gene Name: | TRNT1 |
| UniProt Entry Name: | TRNT1_HUMAN |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
