Anti-TRIM39 Antibody (CAB9977)
- SKU:
- CAB9977
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
| Antibody Name: | Anti-TRIM39 Antibody |
| Antibody SKU: | CAB9977 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human TRIM39 (NP_067076.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | 293T, LO2, K-562, SW480, MCF7 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human TRIM39 (NP_067076.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LVLS EDRK SVKF VETR LRDL PDTP RRFT FYPC VLAT EGFT SGRH YWEV EVGD KTHW AVGV CRDS VSRK GELT PLPE TGYW RVRL WNGD KYAA TTTP FTPL H |
| Gene ID: | 56658 |
| Uniprot: | Q9HCM9 |
| Cellular Location: | Cytoplasm, Mitochondrion, cytosol |
| Calculated MW: | 56kDa/59kDa |
| Observed MW: | 59kDa |
| Synonyms: | TRIM39, RNF23, TFP, TRIM39B |
| Background: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. This gene lies within the major histocompatibility complex class I region on chromosome 6. Alternate splicing results in two transcript variants encoding different isoforms. |
| UniProt Protein Function: | TRIM39: E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1. Belongs to the TRIM/RBCC family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 6p22.1 Cellular Component: cytosol; mitochondrion Molecular Function:identical protein binding; protein binding |
| NCBI Summary: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. This gene lies within the major histocompatibility complex class I region on chromosome 6. Alternate splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9HCM9 |
| NCBI GenInfo Identifier: | 56405385 |
| NCBI Gene ID: | 56658 |
| NCBI Accession: | Q9HCM9.2 |
| UniProt Secondary Accession: | Q9HCM9,Q5STG3, Q5STG4, Q76BL3, Q8IYT9, Q96IB6, |
| UniProt Related Accession: | Q9HCM9 |
| Molecular Weight: | 60kDa |
| NCBI Full Name: | E3 ubiquitin-protein ligase TRIM39 |
| NCBI Synonym Full Names: | tripartite motif containing 39 |
| NCBI Official Symbol: | TRIM39 |
| NCBI Official Synonym Symbols: | TFP; RNF23; TRIM39B |
| NCBI Protein Information: | E3 ubiquitin-protein ligase TRIM39 |
| UniProt Protein Name: | E3 ubiquitin-protein ligase TRIM39 |
| UniProt Synonym Protein Names: | RING finger protein 23; RING-type E3 ubiquitin transferase TRIM39Curated; Testis-abundant finger protein; Tripartite motif-containing protein 39 |
| Protein Family: | E3 ubiquitin-protein ligase |
| UniProt Gene Name: | TRIM39 |
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