Anti-TRHDE Antibody (CAB10300)
- SKU:
- CAB10300
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-TRHDE Antibody |
| Antibody SKU: | CAB10300 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 62-200 of human TRHDE (NP_037513.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | 22Rv1 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 62-200 of human TRHDE (NP_037513.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SLRF DECG ASAT PGAD GGPS GFPE RGGN GSLP GSAR RNHH AGGD SWQP EAGG VASP GTTS AQPP SEEE REPW EPWT QLRL SGHL KPLH YNLM LTAF MENF TFSG EVNV EIAC RNAT RYVV LHAS RVAV EKVQ LAED RAF |
| Gene ID: | 29953 |
| Uniprot: | Q9UKU6 |
| Cellular Location: | Membrane, Single-pass type II membrane protein |
| Calculated MW: | 117kDa |
| Observed MW: | 117kDa |
| Synonyms: | TRHDE, PAP-II, PGPEP2, TRH-DE |
| Background: | This gene encodes a member of the peptidase M1 family. The encoded protein is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone. |
| UniProt Protein Function: | TRHDE: Specific inactivation of TRH after its release. Belongs to the peptidase M1 family. |
| UniProt Protein Details: | Protein type:EC 3.4.19.6; Membrane protein, integral; Protease Chromosomal Location of Human Ortholog: 12q21.1 Cellular Component: cytoplasm; integral to plasma membrane Molecular Function:aminopeptidase activity; peptide binding; zinc ion binding Biological Process: cell-cell signaling; peptide catabolic process; regulation of blood pressure; signal transduction |
| NCBI Summary: | This gene encodes a member of the peptidase M1 family. The encoded protein is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone.[provided by RefSeq, Dec 2008] |
| UniProt Code: | Q9UKU6 |
| NCBI GenInfo Identifier: | 11387208 |
| NCBI Gene ID: | 29953 |
| NCBI Accession: | Q9UKU6.1 |
| UniProt Secondary Accession: | Q9UKU6,Q6UWJ4, A5PL19, |
| UniProt Related Accession: | Q9UKU6 |
| Molecular Weight: | 117kDa |
| NCBI Full Name: | Thyrotropin-releasing hormone-degrading ectoenzyme |
| NCBI Synonym Full Names: | thyrotropin releasing hormone degrading enzyme |
| NCBI Official Symbol: | TRHDE |
| NCBI Official Synonym Symbols: | PAP-II; PGPEP2; TRH-DE |
| NCBI Protein Information: | thyrotropin-releasing hormone-degrading ectoenzyme |
| UniProt Protein Name: | Thyrotropin-releasing hormone-degrading ectoenzyme |
| UniProt Synonym Protein Names: | Pyroglutamyl-peptidase II; PAP-II; TRH-specific aminopeptidase; Thyroliberinase |
| Protein Family: | Thyrotropin-releasing hormone-degrading ectoenzyme |
| UniProt Gene Name: | TRHDE |
 | Western blot analysis of extracts of 22Rv1 cells, using TRHDE antibody (CAB10300) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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