Anti-TPPP Antibody (CAB8574)
- SKU:
- CAB8574
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| Antibody Name: | Anti-TPPP Antibody |
| Antibody SKU: | CAB8574 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-219 of human TPPP (NP_008961.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat, Mouse brain, Mouse pancreas, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-219 of human TPPP (NP_008961.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MADK AKPA KAAN RTPP KSPG DPSK DRAA KRLS LESE GAGE GAAA SPEL SALE EAFR RFAV HGDA RATG REMH GKNW SKLC KDCQ VIDG RNVT VTDV DIVF SKIK GKSC RTIT FEQF QEAL EELA KKRF KDKS SEEA VREV HRLI EGKA PIIS GVTK AISS PTVS RLTD TTKF TGSH KERF DPSG KGKG KAGR VDLV DESG YVSG YKHA GTYD QKVQ GGK |
| Gene ID: | 11076 |
| Uniprot: | O94811 |
| Cellular Location: | Cytoplasm, Nucleus, cytoskeleton |
| Calculated MW: | 23kDa |
| Observed MW: | 24kDa |
| Synonyms: | TPPP, TPPP/p25, TPPP1, p24, p25, p25alpha |
| Background: |
| UniProt Protein Function: | TPPP: May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown. Belongs to the TPPP family. |
| UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 5p15.3 Cellular Component: cytoplasm; microtubule; nucleus; perinuclear region of cytoplasm Molecular Function:microtubule binding; protein binding; tubulin binding Biological Process: microtubule bundle formation; microtubule polymerization; positive regulation of protein complex assembly; positive regulation of protein polymerization |
| UniProt Code: | O94811 |
| NCBI GenInfo Identifier: | 28380097 |
| NCBI Gene ID: | 11076 |
| NCBI Accession: | O94811.1 |
| UniProt Related Accession: | O94811 |
| Molecular Weight: | 23,694 Da |
| NCBI Full Name: | Tubulin polymerization-promoting protein |
| NCBI Synonym Full Names: | tubulin polymerization promoting protein |
| NCBI Official Symbol: | TPPP |
| NCBI Official Synonym Symbols: | p24; p25; TPPP1; TPPP/p25; p25alpha |
| NCBI Protein Information: | tubulin polymerization-promoting protein |
| UniProt Protein Name: | Tubulin polymerization-promoting protein |
| UniProt Synonym Protein Names: | 25 kDa brain-specific protein; TPPP/p25; p24; p25-alpha |
| Protein Family: | TPPP family protein |
| UniProt Gene Name: | TPPP |
| UniProt Entry Name: | TPPP_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TPPP antibody (CAB8574) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded mouse brain using TPPP antibody (CAB8574) at dilution of 1:100 (40x lens). |
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