Anti-TOM1L2 Antibody (CAB20563)
- SKU:
- CAB20563
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Product Name: | TOM1L2 Rabbit pAb |
Product Code: | CAB20563 |
Size: | 50uL, 100uL |
Applications: | WB |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human TOM1L2. |
Applications: | WB |
Recommended Dilutions: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | Mouse brain, Rat brain |
Immunogen: | Recombinant protein of human TOM1L2. |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 146691 |
Uniprot: | Q6ZVM7 |
Calculated MW: | 55kDa |
Observed MW: | 60kDa |
Background: | This gene belongs to a small gene family whose members have an N-terminal VHS domain followed by a GAT domain; domains which typically participate in vesicular trafficking. The canonical protein encoded by this gene also has a C-terminal clathrin binding motif. This protein has been shown to interact with Tollip, clathrin and ubiquitin and is thought to play a role in endosomal sorting. This gene resides in the 3.7 Mb deletion of chromosome region 17p11.2 that is associated with Smith-Magenis syndrome. Alternative splicing results in multiple transcript variants encoding distinct proteins. |