Anti-TMPRSS11D Antibody (CAB10132)
- SKU:
- CAB10132
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-TMPRSS11D Antibody |
| Antibody SKU: | CAB10132 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 42-292 of human TMPRSS11D (NP_004253.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, Mouse liver, Mouse kidney, Mouse skeletal muscle, Rat liver, Rat kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 42-292 of human TMPRSS11D (NP_004253.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | AFDQ KSYF YRSS FQLL NVEY NSQL NSPA TQEY RTLS GRIE SLIT KTFK ESNL RNQF IRAH VAKL RQDG SGVR ADVV MKFQ FTRN NNGA SMKS RIES VLRQ MLNN SGNL EINP STEI TSLT DQAA ANWL INEC GAGP DLIT LSEQ RILG GTEA EEGS WPWQ VSLR LNNA HHCG GSLI NNMW ILTA AHCF RSNS NPRD WIAT SGIS TTFP KLRM RVRN ILIH NNYK SATH ENDI ALVR LENS VTFT KDIH SVC |
| Gene ID: | 9407 |
| Uniprot: | O60235 |
| Cellular Location: | Cell membrane, Secreted, Single-pass type II membrane protein |
| Calculated MW: | 46kDa |
| Observed MW: | 46kDa |
| Synonyms: | TMPRSS11D, HAT |
| Background: | This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. |
| UniProt Protein Function: | TMPRSS11D: May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Belongs to the peptidase S1 family. |
| UniProt Protein Details: | Protein type:Protease; EC 3.4.21.-; Membrane protein, integral Chromosomal Location of Human Ortholog: 4q13.2 Cellular Component: extracellular region Molecular Function:peptidase activity Biological Process: proteolysis; respiratory gaseous exchange |
| NCBI Summary: | This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60235 |
| NCBI GenInfo Identifier: | 17376886 |
| NCBI Gene ID: | 9407 |
| NCBI Accession: | O60235.1 |
| UniProt Secondary Accession: | O60235,Q08AF6, |
| UniProt Related Accession: | O60235 |
| Molecular Weight: | 46,263 Da |
| NCBI Full Name: | Transmembrane protease serine 11D |
| NCBI Synonym Full Names: | transmembrane protease, serine 11D |
| NCBI Official Symbol: | TMPRSS11D |
| NCBI Official Synonym Symbols: | HAT |
| NCBI Protein Information: | transmembrane protease serine 11D |
| UniProt Protein Name: | Transmembrane protease serine 11D |
| UniProt Synonym Protein Names: | Airway trypsin-like protease |
| Protein Family: | Transmembrane protease serine |
| UniProt Gene Name: | TMPRSS11D |
| UniProt Entry Name: | TM11D_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TMPRSS11D antibody (CAB10132) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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