Anti-TMPRSS11A Antibody (CAB8605)
- SKU:
- CAB8605
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| Antibody Name: | Anti-TMPRSS11A Antibody |
| Antibody SKU: | CAB8605 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-421 of human TMPRSS11A (NP_872412.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, A-549, SW620, Mouse liver, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-421 of human TMPRSS11A (NP_872412.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SASF QPNL TVHI TGFG ALYY GGES QNDL REAR VKII SDDV CKQP QVYG NDIK PGMF CAGY MEGI YDAC RGDS GGPL VTRD LKDT WYLI GIVS WGDN CGQK DKPG VYTQ VTYY RNWI ASKT GI |
| Gene ID: | 339967 |
| Uniprot: | Q6ZMR5 |
| Cellular Location: | Membrane, Single-pass type II membrane protein |
| Calculated MW: | 47kDa |
| Observed MW: | 48kDa |
| Synonyms: | TMPRSS11A, ECRG1 |
| Background: |
| UniProt Protein Function: | TMPRSS11A: Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest. Belongs to the peptidase S1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; EC 3.4.21.-; Protease Chromosomal Location of Human Ortholog: 4q13.2 Cellular Component: integral to plasma membrane; extracellular region Molecular Function:serine-type endopeptidase activity Biological Process: proteolysis; cell cycle |
| UniProt Code: | Q6ZMR5 |
| NCBI GenInfo Identifier: | 167466252 |
| NCBI Gene ID: | 339967 |
| NCBI Accession: | NP_001107859.1 |
| UniProt Secondary Accession: | Q6ZMR5,Q2NKI9, Q6JE90, Q7RTY4, Q86TK8, J3KNQ8, |
| UniProt Related Accession: | Q6ZMR5 |
| Molecular Weight: | 47,254 Da |
| NCBI Full Name: | transmembrane protease serine 11A isoform 2 |
| NCBI Synonym Full Names: | transmembrane protease, serine 11A |
| NCBI Official Symbol: | TMPRSS11A |
| NCBI Official Synonym Symbols: | ECRG1 |
| NCBI Protein Information: | transmembrane protease serine 11A |
| UniProt Protein Name: | Transmembrane protease serine 11A |
| UniProt Synonym Protein Names: | Airway trypsin-like protease 1; Epidermal type-II transmembrane serine protease; Esophageal cancer-susceptibility gene 1 protein |
| UniProt Gene Name: | TMPRSS11A |
| UniProt Entry Name: | TM11A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TMPRSS11A antibody (CAB8605) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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