Anti-THSD4 Antibody (CAB17773)
- SKU:
- CAB17773
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-THSD4 Antibody |
| Antibody SKU: | CAB17773 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human THSD4 (NP_079093.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | SH-SY5Y |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human THSD4 (NP_079093.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | AEGP TNEI LDVY MIHQ QPNP GVHY EYVI MGTN AISP QVPP HRRP GEPF NGQM VTEG RSQE EGEQ KGRN EEKE DLRG EAPE MFTS ESAQ TFPV RHPD RFSP HRPD NLVP PAPQ PPRR SRDH NWKQ LGTT ECST TCGK GSQY PIFR CVHR STHE EAPE SYCD SSMK PTPE EEPC NIFP CPAF WDIG EWSE CSKT CGLG MQHR Q |
| Gene ID: | 79875 |
| Uniprot: | Q6ZMP0 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 112kDa |
 | Western blot - THSD4 Polyclonal Antibody (CAB17773) |
| Synonyms: | ADAMTSL-6, ADAMTSL6, FVSY9334, PRO34005, THSD4 |
| Background: |
| UniProt Protein Function: | THSD4: Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Protease; Secreted; Extracellular matrix; Secreted, signal peptide Chromosomal Location of Human Ortholog: 15q23 Cellular Component: microfibril Molecular Function:metalloendopeptidase activity Biological Process: elastic fiber assembly; proteolysis |
| UniProt Code: | Q6ZMP0 |
| NCBI GenInfo Identifier: | 556695454 |
| NCBI Gene ID: | 79875 |
| NCBI Accession: | NP_001273358.1 |
| UniProt Secondary Accession: | Q6ZMP0,Q6MZI3, Q6UXZ8, Q9H8E4, B2RTY3, B4DR13, |
| UniProt Related Accession: | Q6ZMP0 |
| Molecular Weight: | 73,408 Da |
| NCBI Full Name: | thrombospondin type-1 domain-containing protein 4 isoform 2 |
| NCBI Synonym Full Names: | thrombospondin, type I, domain containing 4 |
| NCBI Official Symbol: | THSD4 |
| NCBI Official Synonym Symbols: | ADAMTSL6; FVSY9334; PRO34005; ADAMTSL-6 |
| NCBI Protein Information: | thrombospondin type-1 domain-containing protein 4 |
| UniProt Protein Name: | Thrombospondin type-1 domain-containing protein 4 |
| UniProt Synonym Protein Names: | A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6; ADAMTS-like protein 6; ADAMTSL-6 |
| Protein Family: | Thrombospondin type-1 domain-containing protein |
| UniProt Gene Name: | THSD4 |
| UniProt Entry Name: | THSD4_HUMAN |
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